YRC Public Data Repository - Protein Structure Prediction

Protein:	dpb4
Organism:	Schizosaccharomyces pombe
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dpb4.

Description	E-value	Query Range	Subject Range
gi\|114646579 - gi\|114646579\|ref\|XP_509327.2\| PREDICTED: similar to Nuclear transcription factor Y, beta [Pan troglo...	202.0	[0..2]	[166..36]
gi\|38156576, gi\|... - gi\|38156576\|gb\|AAR12910.1\| nuclear transcription factor-Y B subunit 3 [Bufo gargarizans], gi\|3815657...	199.0	[0..2]	[166..43]
gi\|147901227, gi... - gi\|3170225\|gb\|AAC82336.1\| nuclear Y/CCAAT-box binding factor B subunit NF-YB [Xenopus laevis], gi\|14...	199.0	[0..2]	[166..43]
NFYB_CHICK - Nuclear transcription factor Y subunit beta OS=Gallus gallus GN=NFYB PE=2 SV=2	197.0	[0..2]	[166..42]
gi\|60653441 - gi\|60653441\|gb\|AAX29415.1\| nuclear transcription factor Y beta [synthetic construct]	197.0	[0..2]	[166..44]
NFYB_BOVIN - Nuclear transcription factor Y subunit beta OS=Bos taurus GN=NFYB PE=2 SV=1	196.0	[0..2]	[166..44]
gi\|105492, gi\|35050 - gi\|35050\|emb\|CAA42230.1\| CAAT-box DNA binding protein subunit B (NF-YB) [Homo sapiens], gi\|105492\|pi... gi\|109098520, gi... - gi\|109098520\|ref\|XP_001097495.1\| PREDICTED: similar to Nuclear transcription factor Y subunit beta (...	196.0	[0..2]	[166..42]
ENSMMUT000000317... - null, null NFYB - nuclear transcription factor Y, beta ENSCJAT00000028469 - null gi\|123993257, gi... - gi\|60656481\|gb\|AAX32804.1\| nuclear transcription factor Y beta [synthetic construct], gi\|208966894\|d...	196.0	[0..2]	[166..44]
gi\|12848141 - gi\|12848141\|dbj\|BAB27844.1\| unnamed protein product [Mus musculus]	196.0	[0..2]	[166..6]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQDKSKETS ELDDLALPRS IIMRLVKGVL PEKSLVQKEA LKAMINSATL FVSFLTSASG  60
   61 EIATNNNRKI LMPQDVLNAL DEIEYPEFSK TLKKHLEAYE LALKEKRLKL PNVSDVDNRK 120
  121 KAKIDAHDTT PLDEEKDELE EERIAEDIAQ NEVEQNIDDV EDLEEVNDTL DANAESPQIE 180
  181 TIHLTDATGN PIEDSSESDS EESLQLNDSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.522879
Match:	1jfiB
Description:	Negative cofactor 2, NC2, beta chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA-directed DNA polymerase activity	7.30463919195401	bayes_pls_golite062009
DNA polymerase activity	7.25909396656216	bayes_pls_golite062009
nucleotidyltransferase activity	4.91761894051618	bayes_pls_golite062009
DNA binding	3.33590750206299	bayes_pls_golite062009
nucleic acid binding	3.33150991098513	bayes_pls_golite062009
transcription regulator activity	2.74104602193943	bayes_pls_golite062009
binding	2.68226682911828	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	2.18081531032351	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.71814239259767	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.71244156762178	bayes_pls_golite062009
transferase activity	1.4922191078713	bayes_pls_golite062009
transcription factor activity	1.43258372806556	bayes_pls_golite062009
transcription activator activity	0.56890094816403	bayes_pls_golite062009
transcription factor binding	0.48055497002898	bayes_pls_golite062009
protein binding	0.38229791767081	bayes_pls_golite062009
transcription cofactor activity	0.36684586697198	bayes_pls_golite062009
transcription repressor activity	0.0502944474168801	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: