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Protein Overview: erf1

General Information:
Name(s) found: erf1 / SPCC18B5.06 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • translation release factor eRF1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 390 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ICLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [ISS]
    translation [ISSLink to PubMed article]
    Molecular Function: endonuclease activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLIQKNIEK NGSGWITMCP EEPEDMWHLY NILQVGDQLK ASTVRRVVKV GATGSTSGSR  60
   61 VVMKLRILVE NMDFDTKAAQ LHIKGRTTEY HPEVKMGSYH TLDLELHRNF TLYKNEWDAF 120
  121 ALDRVDAACN PSRNAEIGAV VLDEGLANIC LITDYMTILR QRIDQVIPRK RRGDSSAYQK 180
  181 GLDKFYDSVF QSINSEFDFD KLKVVILASP GFVARGLYDY IFSMAVKLDL KQIVKSKNKF 240
  241 VILHSSTGHI HSLNEILKDP AVESKLADTK YVQEIRVLNK FYDVMNEDDR KAWYGPNHVL 300
  301 KAFELGAIGE LLISDSLFRS SDIATRKKWV SLVEGVKEIN CPVYIFSSLH ESGKQLDLLS 360
  361 GIAAILTYPV DEEDISEDEE DEESQNFEHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..390] PSI-BLAST 124.0 Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1; C-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1; N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.8176240743328 bayes_pls_golite062009
  • translation release factor activity
    		•  3.48975835887408 bayes_pls_golite062009
  • translation termination factor activity
    		•  3.46050614877315 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  2.50763528378297 bayes_pls_golite062009
  • binding
    		•  2.24516466558786 bayes_pls_golite062009
  • structural molecule activity
    		•  2.17996532926344 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09371417164502 bayes_pls_golite062009
  • translation regulator activity
    		•  1.83257472130927 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.81472167858216 bayes_pls_golite062009
  • mRNA binding
    		•  1.38466459724533 bayes_pls_golite062009
    		• 1.36644447800624 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.519765773143644 bayes_pls_golite062009
  • protein binding
    		•  0.381324299701367 bayes_pls_golite062009
  • hydrolase activity
    		•  0.341035995293011 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle