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A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends. The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells. The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap. The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
Acc: GO:0000294
Aspect: Biological Process
Desc: A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends.
Synonyms:
  • mRNA catabolic process, endonucleolytic
  • mRNA catabolism, endonucleolytic
  • nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay
  • endonucleolytic mRNA decay
  • mRNA breakdown, endonucleolytic cleavage-dependent decay
  • mRNA degradation, endonucleolytic cleavage-dependent decay
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000294 - nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle