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Protein Overview: rgf3

General Information:
Name(s) found: rgf3 / SPCC645.06c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • RhoGEF Rgf3 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1275 amino acids

    Gene Ontology:
    Cellular Component: cell division site [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: regulation of Rho protein signal transduction [IGILink to PubMed articleLink to PubMed article]
    regulation of cell separation during cytokinesis [IMPLink to PubMed article]
    regulation of catalytic activity [ICLink to PubMed article]
    regulation of ascospore wall 1,3-beta-glucan biosynthetic process [ICLink to PubMed article]
    primary cell septum disassembly [IMPLink to PubMed article]
    regulation of 1,3-beta-glucan biosynthetic process [IMPLink to PubMed article]
    actin cortical patch localization [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSNELFHR SSKDHGGKSR ICLDSSEDTY PPHSSSPPSF QKRLSFSDFS TTRLFSPPFL  60
   61 SKRSNNSPHR FSYSPPQHPA SINSRRVASY TVQSSPSRTT YRQLPNEPQN SAAYTTYSSF 120
  121 PNALFDDFSP NNPLDTDPFL TSPGNKQNTV DSFRPLPETP VSPGGSLVHP LPRPPLPSSV 180
  181 SSHSSPYSTT SSTSLYSLYN DISLSCSPEP YLPLSPTRSP ARTPSPIRLY SSDALRPQSP 240
  241 LSPSVEYLTP PNPYSLKSDI SSTRQLPKIP VQDYASGKIS SPLITRTHRR AQSETLFSSC 300
  301 REPWLVGKLY KWCKEEVFTA LGGLVHEGVS RREVAQVMAT LFTIHIASME FLIAEIIAKN 360
  361 ILGDWINYGL VEVINLEKLQ IAFTSNEPPS GSGVLPFLTN GGCYSYICRS RSCPSKYQCY 420
  421 SCRCARNSSL EFTSLPGQSS DTWSIFWNIS SLNSLPSSLS KREIARQNNI HELICKESDY 480
  481 VADLNTLAEL FRDGIVQQQD AIVPSNRVAD FIQSVFGNVE SIRQLHSRLF LPQLIMRERL 540
  541 QGPVVSIIGD ILLEWIHAAK SSYINYAKQF PLADETYKLE CQRNTYFARW LAACRSDPRC 600
  601 RRLDFQHFLQ RPTQRLQRYT LELDTILKHT EQSSWDFQLI TQAVKELRAT CEECDAVIAT 660
  661 VLEANRIRDL SYQLLFKNHE SVNLELRDPE REFFFEGIVQ RRSDSRLDWL DIHLFLLDNY 720
  721 LIMAKARKDK RTNASRYVVS KRPIPLDLLV LSPKMDDFQL KSNTNKFLGS LAGNLPQESL 780
  781 TTKSKRKSKV NLELMFDATA EKNNENSMNS AVFEKSQLYP FTIRHLGAYT ASYTLYVESL 840
  841 QLRKLWVEKI NVAKKRHSQK INIKNPFALK VVSDVAFQYP PSDLVNGNEP LNSFNEITLV 900
  901 EGSSIDRALN EVAWKHPIVS EELLPEPIAY GDISCIAQFN DYEGHVSVLI ATSTGIFLGA 960
  961 FGDSSDIRDW KKISSQRRVT QLGVVEEFDI LLELRDKTLY AHKLSRIIEM GLIESKIAVV1020
 1021 IGTPHAVSFF KIGKLSEGAS VKRERTLVFY KEGLGNTTTI ICCEPVIGLG HNYQKTYAFK1080
 1081 RKDVTSFRTL DDFHVTANCH SIDCFKYSIA LCHNKGIDVL RLDPKLAVGF PSPSVLNDTL1140
 1141 FRNRINNSKP LGVFRIHDPS LFACCYQFGA VFVNGEGSMV NKECWFDWIG KPNSVTSCHG1200
 1201 YLIAFNDEFV EIWNTRTRKL NQIIQGNDIK YYPSNSDWLA NGKYIMFGMV HPQYHDRHLI1260
 1261 LALNKAKTNS FIIED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 5.69897 No description for 1y0fA was found.
    2 View Details [375..462] PSI-BLAST 87.154902 No description for 2pz1A was found.
    3 View Details [463..987] PSI-BLAST 28.69897 Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang.
    4 View Details [988..1128] deduced N/A No confident structure predictions are available.
    5 View Details [1129..1275] MSA 2.085976 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.65091781683225 bayes_pls_golite062009
  • protein binding
    		•  2.12168271674167 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.66986263418539 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.64990514605397 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  1.31154393866945 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.2550809703725 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.25381967078645 bayes_pls_golite062009
  • small GTPase binding
    		•  0.8507658747425 bayes_pls_golite062009
  • GTPase binding
    		•  0.82889812790119 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.745321902095093 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.66119387669652 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.593146992671847 bayes_pls_golite062009
  • DNA binding
    		•  0.48667544658785 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle