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Protein Overview: phx1

General Information:
Name(s) found: phx1 / SPAC32A11.03c [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • homeobox transcription factor Phx1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 942 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromatin [NASLink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IGILink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: DNA binding [TASLink to PubMed article]
    transcription factor activity [TASLink to PubMed article]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSYSNPENG GQINDNINYS EKRPTMLPEN LSLSNYDMDS FLGQFPSDNN MQLPHSTYEQ  60
   61 HLQGEQQNPT NPNYFPPEFD ENKVDWKQEK PKPDAPSFAD NNSFDNVNSS KLTNPSPVQP 120
  121 NIVKSESEPA NSKQNEVVEA TSVEKAKENV AHESGTPESG GSTSAPKSKK QRLTADQLAY 180
  181 LLREFSKDTN PPPAIREKIG RELNIPERSV TIWFQNRRAK SKLISRRQEE ERQRILREQR 240
  241 ELDSLNQKVS QAFAHEVLST SPTSPYVGGI AANRQYANTL LPKPTRKTGN FYMKSGPMQS 300
  301 SMEPCIAESD IPIRQSLSST YYNSLSPNAV PVSSQRKYSA SSYSAIPNAM SVSNQAFDVE 360
  361 SPPSSYATPL TGIRMPQPES DLYSYPREVS PSSGGYRMFG HSKPSSYKAS GPVRPPNMAT 420
  421 GHMRTSSEPT SYDSEFYYFS CTLLVIGLWK RLRASPQDLM CFYSPPKKLF AYLIQFQGIQ 480
  481 YRIEYSFFVI ESIHVFRVEE PLLNELSATA SSRDKPAPNE YWLQMDIQLS VPPVFHMITS 540
  541 EGQGNCTDFT EGNQASEVLL HSLMGRATSM FQMLDRVRRA SPELGSVIRL QKGLNPHQFL 600
  601 DPQWANQLPR QPDSSVFDHQ GRNPPIQGLS HDTSSEYGNK SQFKRLRSTS TPARQDLAQH 660
  661 LLPPKTNTEG LMHAQSVSPI TQAMKSANVL EGSSTRLNSY EPSVSSAYPH HNLALNLDNT 720
  721 QFGELGTSNI SYPLSAPSDV GSLPRASNSP SRPVMHPNTQ GINTEIKDMA AQFPNSQTGG 780
  781 LTPNSWSMNT NVSVPFTTQN REFGGIGSSS ISTTMNAPSQ QLSQVPFGDV SLATENSVPS 840
  841 YGFEVPSEES VYAQARTNSS VSAGVAPRLF IQTPSIPLAS SAGQDSNLIE KSSSGGVYAS 900
  901 QPGASGYLSH DQSGSPFEDV YSPSAGIDFQ KLRGQQFSPD MQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] deduced N/A No confident structure predictions are available.
    2 View Details [140..237] PSI-BLAST 18.0 Homeobox protein hox-b1
    3 View Details [238..429] MSA 4.665997 View MSA. No confident structure predictions are available.
    4 View Details [430..603] MSA 1.142968 View MSA. No confident structure predictions are available.
    5 View Details [604..847] deduced N/A No confident structure predictions are available.
    6 View Details [848..942] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle