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Protein Overview: kap114

General Information:
Name(s) found: kap114 / SPAC22H10.03c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • karyopherin Kap14 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 986 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDALink to PubMed article]
    nucleus [IDALink to PubMed articleLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nuclear pore [RCALink to PubMed article]
    Biological Process: nucleocytoplasmic transport [TASLink to PubMed article]
    protein targeting [RCALink to PubMed article]
    intracellular protein transport [IEA]
    Molecular Function: GTP binding [NASLink to PubMed article]
    protein transporter activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVESKIIKLL EQVQSADPNS RIQAELGLRD LEKYHDFAAK LTDIASSGAS VPLRQGSLIY  60
   61 LQRYIVHHWS PLFEQFQDGP IPDENVKKHV RETLLHLLVS LDNFTLIKAV AYAVSLIANV 120
  121 DYPDEWPEVV PAVLHLLQST NENSINASLD VLDELVDESL VEEQFFIIAP QLASILYQFI 180
  181 FSAPPNDSMR MLQARGIKLF RSCLELIEIY KETKAEHVRV FLEQILPPWM DMFSHKFEVS 240
  241 LVDDRQVILP DSCGYFCIMG EIAMTLTKLR ELFPSKLTPY VVTFVELVWN IIEKLLDPYI 300
  301 REVVFSDGLD DSAFGDKYPI RYLVELLLFV SVALQSKFVQ NLFVSNTVPV PPLPPCIPLL 360
  361 VQYTQLPKHQ IEVYESDVSE YIANEFSMDF ASDTVRGAAI SVLSAFEEHT TLPIQQSLRE 420
  421 MSATYILNNE INWIYQEALL YACCSVDAAS DDTYDDYLDP IYEAIKVRID YSDAPILLLS 480
  481 RFFLFIGYFS ESTVVASQFF QIIMNNLVNA LQVDTVQYAA MKAIERFCSV GKVKPILSLQ 540
  541 PMILEVLSQY ASKSSDEALV LLVEAISSAV KLDCAKAAEL GNSVIPLLFN LVATNASDPY 600
  601 ICGIIEDTFE DIIHAANNYE SMCEITLPEL LQVLNQEDPI MVNIGATLLS CLIRAGPSPL 660
  661 PNGFVGYVLP PVYKITQIHS GDTELLQLSQ EILKGLLEKD TPQLLETEIS GSSGFQYILF 720
  721 ILHQLLDKES DDSACFLVGP ILLELADHAS QMVDLQSILL SCIKRLAIAE QPRFIQSIIY 780
  781 VFAKLIVKDS LGMMHFLTSS LLNEQGLTAF EVLMTVWCDN FVYFSNFKNI SIICIAMTKI 840
  841 YSFDSPLLDS VQVKGELISH SNRIITRSQS KLHPEEYSYV SVGEKILRLL SEEFVSLSKD 900
  901 AIVEEVSDDG ADDWDDGPIS AETFGLSAND EFSGVDNSED EDNTDLQFYL LEFFKEAMKS 960
  961 NLHNINEVVF RLPQEEQDAL VQIKEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..986] PSI-BLAST 111.0 Karyopherin beta2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  4.58709163830613 bayes_pls_golite062009
  • binding
    		•  3.63805603287848 bayes_pls_golite062009
  • transporter activity
    		•  2.92319684675174 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  2.74547353635661 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.40193469608002 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.34284977509828 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  1.91487015967262 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.70521460039069 bayes_pls_golite062009
  • protein binding
    		•  1.63705839411934 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.6217303285315 bayes_pls_golite062009
  • DNA binding
    		•  1.55552983744023 bayes_pls_golite062009
  • nuclear export signal receptor activity
    		•  1.29390474721722 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.20870827474803 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887427876407589 bayes_pls_golite062009
  • signal sequence binding
    		•  0.57106697498903 bayes_pls_golite062009
  • mRNA binding
    		•  0.46864854653143 bayes_pls_golite062009
  • RNA binding
    		•  0.40024158562931 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.106230318891928 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle