Protein Overview: SPBC12C2.05c

General Information:
Name(s) found:	SPBC12C2.05c [Sanger Pombe]
Description(s) found: Found 17 descriptions. SHOW ALL	diacylglycerol binding protein Bzz1 [Sanger Pombe]
Organism:	Schizosaccharomyces pombe
Length:	642 amino acids
Gene Ontology:
Cellular Component:	cell division site [IDA] cell tip [IDA] cytoplasm [ISS] actin cortical patch [ISS]
Biological Process:	actin filament organization [ISS] endocytosis [ISS]
Molecular Function:	zinc ion binding [IEA] diacylglycerol binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLETYKFSD ELHDDFKVVD SWINNGAKWL EDIQLYYKER SSIEKEYAQK LASLSNKYGE  60
   61 KKSRKSSALS VGDTPAMSAG SLECASLTTW SKILDELTRS SKTHQKLSDD YSLDIAEKLK 120
  121 KLESHIEALR KVYDDLYKKF SSEKETLLNS VKRAKVSYHE ACDDLESARQ KNDKYREQKT 180
  181 QRNLKLSESD MLDKKNKYLL RMLVYNAHKQ KFYNETLPTL LNHMQVLNEY RVSNLNEIWC 240
  241 NSFSIEKSLH DTLSQRTVEI QSEIAKNEPV LDSAMFGRHN SKNWALPADL HFEPSPIWHD 300
  301 TDALVVDGSC KNYLRNLLVH SKNDLGKQKG ELVSLDSQLE GLRVDDPNSA NQSFESKKAS 360
  361 INLEGKELMV KARIEDLEVR INKITSVANN LEEGGRFHDF KHVSFKLPTS CSYCREIIWG 420
  421 LSKRGCVCKN CGFKCHARCE LLVPANCKNG EPEVADDDAV DTSVTATDDF DASASSSNAY 480
  481 ESYRNTYTDD MDSSSIYQTS LSNVKTEETT PAEPASKVDG VVLYDFTGEH EGVITASEGQ 540
  541 EFTLLEPDDG SGWVRVKIDG TDGLIPASYV KLNDELNTSV TLDGDSSYVK ALYAYTAQSD 600
  601 MELSIQEGDI IQVTNRNAGN GWSEGILNGV TGQFPANYVT DV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..306]	PSI-BLAST	16.522879	No description for 2eflA was found.
2	View Details	[307..365]	deduced	N/A	No confident structure predictions are available.
3	View Details	[366..513]	FFAS03	2.85	NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
4	View Details	[514..642]	PSI-BLAST	15.69897	Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
cytoskeletal protein binding	2.86582611923959	bayes_pls_golite062009
binding	2.2879693624429	bayes_pls_golite062009
protein binding	2.08046860800611	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.533946913012306	bayes_pls_golite062009
pyrophosphatase activity	0.492863553428448	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.48203970262288	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.481384553079895	bayes_pls_golite062009

2

No functions predicted.

3

Term	Confidence	Notes
binding	2.13567713176414	bayes_pls_golite062009
protein binding	1.417409982197	bayes_pls_golite062009
GTPase regulator activity	0.852428113024117	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	0.590904037542168	bayes_pls_golite062009
myosin heavy chain kinase activity	0.433378144372842	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	0.36934922714234	bayes_pls_golite062009
diacylglycerol binding	0.161261456004319	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.117036271102062	bayes_pls_golite062009

4

Term	Confidence	Notes
actin binding	4.94949685871786	bayes_pls_golite062009
cytoskeletal protein binding	4.41722924924158	bayes_pls_golite062009
actin filament binding	3.69427077755816	bayes_pls_golite062009
binding	2.55003340159545	bayes_pls_golite062009
protein binding	2.35325421236395	bayes_pls_golite062009
structural constituent of muscle	1.44117328570973	bayes_pls_golite062009
structural constituent of cytoskeleton	0.371928447183203	bayes_pls_golite062009
protein binding, bridging	0.230308623372106	bayes_pls_golite062009
molecular adaptor activity	0.211510977251932	bayes_pls_golite062009
transporter activity	0.0502941720831361	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle