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Protein Overview: SPBC2F12.05c

General Information:
Name(s) found: SPBC2F12.05c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • sterol binding ankyrin repeat protein [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1310 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    endoplasmic reticulum [ISSLink to PubMed article]
    protein complex [RCALink to PubMed article]
    Biological Process: sterol transport [ISS]
    steroid metabolic process [IEA]
    cellular response to stress [IEPLink to PubMed article]
    endocytosis [ISS]
    exocytosis [ISS]
    Molecular Function: oxysterol binding [ISSLink to PubMed article]
    phosphatidylinositol binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHPSPDSVS STSSSDHKKA ELSDSLKQLQ LLQAFQAGDI KQVDNLLHNK SKDECTHALF  60
   61 ISIQCANVQM VKHILSVFDV DVNAYDKNKN TPLHLAAMAG RQDIVEALLL HPDINYNLVN 120
  121 ANNKKAYQVA TSPQLMDFMK GFYVTYTKET AREFKKAFKE RNLESMDYLM RHNEFNDAID 180
  181 LNEVDIKTGQ TYLHVATKAK DAELVKWLLD NGADPYRRDK FGKLPTDYTK DENMRSLLRS 240
  241 YSGNRDSSSA PAVPQHMSGY LKKWTNYKSG YKLRWFTLNN GVLSYYKNQD DASSACRGSI 300
  301 NLKLARLVHD PKQPTVFQVI GKGSVRYSVK ANSPVEAKKW IAAISSAIEN DEEANKPNVT 360
  361 ADNASFGTHD LAPAAHKFTQ SNASGNSGWD DNESDIDRAQ LPSRENFEFN VNIAKLQVET 420
  421 LHKLIDSAMQ TEKVKKDPSL SQVFDGISNS FNTLHKTVLE MLDLQRQAEH YYKRKLDNAK 480
  481 AINALWAENL KTVVEEQDQI EERYHRSEAH RRRTKRAFRR LAASLKKRPS DKDNKLHIHY 540
  541 DDGAMSSTSY STDFTDDEEE TNTKDEFFDV DAHDNNHANK AEPSQTANNV HEIREPSFSS 600
  601 EHKPQPSLKT TTDVSSPETK QNIADIRKTT LTDQTEEFTE RRDNNGSIPS KQPSDEQHLG 660
  661 KESLPSQQST VSNHHRKESI PSKQPTEGQH ARQESLPSQQ TTETKHLRKE STPSKQPTEG 720
  721 QHTRQESLPS QQTTETKHLR KESIPSKQPT EGQHARQESL PSQQTTETKH LRKESIPSKQ 780
  781 PSGGQQLRQE SLPSQQSSES KQSTQHQQPV EVQKSIQSDV SAPKAKEVSE KPVSHQAKPS 840
  841 NASQLSRNTD DTQAKEAPKE ASIPDNASTA STKVSNDSHL KPDADKKSVS SELTHASKPS 900
  901 LDEKTMQLAK QIAVSFHGYE APTRENLDVN DDRPKISLWG ILKGMIGKDM TKMTLPVSFN 960
  961 EPTSLLQRVA EDMEYTELLD QASHNKDPYQ RILYVAAFAA SEYASTLNRV AKPFNPLLGE1020
 1021 TYEFCHPQRG FRFIVEQVSH HPPVGAAYSE SANWKYYGES SVKSKFYGKS FDISPLGTWF1080
 1081 LELRHPSGEV ELYTWKKVTS SVVGIILGSP SVDNYGQMHI VNHSSGINCV LDFKPRGWRG1140
 1141 TNAHEVKGSV QSTDDTPKWM VNGHWNDKIF GQQPNGNKIL LWQNHERPPR PFNLTPFAIS1200
 1201 LNALTPQLKP WLPPTDTRLR PDQRAMENGQ YDLAASEKNR LEEKQRKKRR MREQGEMPPW1260
 1261 SPRWFSAAKH PVTGEDYWQF NNEYWKIREE AGEAHLAGKE FEWPNVDDIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..467] PSI-BLAST 66.69897 Ankyrin-R
    2 View Details [468..694] deduced N/A No confident structure predictions are available.
    3 View Details [695..917] deduced N/A No confident structure predictions are available.
    4 View Details [918..1310] PSI-BLAST 80.69897 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.74306164317133 bayes_pls_golite062009
  • protein binding
    		•  1.6716587413544 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
    		• 0.35288515581255 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle