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Protein Overview: SPAC4G9.02

General Information:
Name(s) found: SPAC4G9.02 [Sanger Pombe]
Description(s) found:
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  • pir||T38861 hypothetical protein SPAC4G9.02 - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • gi|19114596|ref|NP_593684.1| ribonuclease H2 complex subunit [Schizosaccharomyces pombe 972h-] [NCBI NR]
  • gi|1723422|sp|Q10236.1|RNH2A_SCHPO RecName: Full=Ribonuclease H2 subunit A; Short=RNase H2 subunit A; AltName: Full=Ribonuclease HI subunit A; AltName: Full=Ribonuclease HI large subunit; Short=RNase HI large subunit [NCBI NR]
  • gi|1204203|emb|CAA93552.1| ribonuclease H2 complex subunit Rnh201 (predicted) [Schizosaccharomyces pombe] [NCBI NR]
  • ribonuclease H2 complex subunit [Sanger Pombe]
  • (Q10236) Probable ribonuclease HI large subunit (EC 3.1.26.4) (RNase HI large subunit) (RNase H(35)) [Swiss-Prot]
  • Ribonuclease H2 subunit A OS=Schizosaccharomyces pombe GN=rnh201 PE=2 SV=1 [Swiss-Prot]
  • PUTATIVE RIBONUCLEASE H ENDONUCLEASE; POSSIBLY DEGRADES RNA IN RNA-DNA HYBRIDS; SIMILAR TO S. CEREVISIAE RNH35: Q10236; [pompepVF.fasta]
  • PUTATIVE RIBONUCLEASE H, ENDONUCLEASE THAT DEGRADES RNA IN RNA-DNA HYBRIDS; BY SIMILARITY TO YEAST RNH35: Q10236; [pompepV13]
  • Probable ribonuclease HI large subunit (EC 3.1.26.-) (RNase HI large subunit) (RNase H(35)) [pompep4896]
  • |||putative Ribonuclease H endonuclease [pompepnew.fasta]
  • |||ribonuclease H|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • hypothetical protein [Schizosaccharomyces pombe]gi|1204203|emb|CAA93552.1| SPAC4G9.02 [Schizosaccharomyces pombe]gi|1723422|sp|Q10236|RNHL_SCHPO Probable ribonuclease HI large subunit (RNase HI large subunit) (RNase H(35))gi|7491151|pir||T38861 hypothe [nrdb_11152004_Chlamydomonas]
  • (Q10236) Probable ribonuclease HI large subunit (EC 3.1.26.-) (RNase HI large subunit) (RNase H(35)) [pompep4896_normal_reversed]
  • |rnh201||ribonuclease H2 complex subunit Rnh201 |Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Ribonuclease H2 subunit A (RNase H2 subunit A) (Ribonuclease HI subunit A) (Ribonuclease HI large subunit) (RNase HI large subunit) [nr-271106-contam.fasta]
  • SPAC4G9.02 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • hypothetical protein SPAC4G9.02 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • Ribonuclease H2 subunit A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rnh201 PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 326 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    ribonuclease H2 complex [ISSLink to PubMed article]
    Biological Process: DNA-dependent DNA replication [ISSLink to PubMed article]
    DNA replication, removal of RNA primer [ICLink to PubMed article]
    Molecular Function: ribonuclease H activity [ISSLink to PubMed article]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDDHDAWEP EELVSDNNSS ENELQEDQNS SITFLPPSVN KSNPAKSNYY HSTVTDDISK  60
   61 SQPYRLGVDE AGRGPVLGPM VYAVAYCPVD FDLTNYGFAD SKTLASLKRE ELLKLICNKS 120
  121 NELGKNVGWS TMSISARELA AGMLRYRNKY NLNLQAHDTT IDLIKKVYES GINVTEIYVD 180
  181 TVGPPISYQE KLQAHFPQAK VTVTKKADSL FPIVSLASIC AKVTRDIQLE CARESIRTEN 240
  241 WGSGYSSDAR TTEWLKVNVD KIFGWKGDIV RYSWKTAKDL LELPSKSQSS IEIDWHEDDD 300
  301 TPTLNFTQKK KPNPASRSWF GSEFYF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..326] PSI-BLAST 47.69897 Crystal structure of the ribonuclease H2 from Pyrococcus horikoshii OT3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease H activity
    		•  8.30690368719529 bayes_pls_golite062009
  • ribonuclease activity
    		•  4.81599779544001 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.01417328311605 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.89077854960958 bayes_pls_golite062009
  • exonuclease activity
    		•  2.86892175148145 bayes_pls_golite062009
  • nuclease activity
    		•  2.84202779131927 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78602644579272 bayes_pls_golite062009
  • DNA polymerase activity
    		•  2.75375255857158 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  2.66279543366449 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.57498413015114 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  2.49957333962564 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.94077739152313 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.87431870698721 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.12401205867904 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.12235348738959 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10433412699603 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.86862629020506 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.782108781904855 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.77421125364834 bayes_pls_golite062009
  • binding
    		•  0.762139256580538 bayes_pls_golite062009
  • DNA binding
    		•  0.710663468386339 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.708753843279937 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.598360955770972 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  0.48776342704945 bayes_pls_golite062009
  • transcription factor activity
    		•  0.332903382446869 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle