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View Structure Prediction Details

Protein: SPAC4G9.02
Organism: Schizosaccharomyces pombe
Length: 326 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC4G9.02.

Description E-value Query
Range
Subject
Range
gi|42547584, gi|... - gi|46107902|ref|XP_381010.1| hypothetical protein FG00834.1 [Gibberella zeae PH-1], gi|42547584|gb|E...
267.0 [0..15] [322..1]
RNH2A_RAT - Ribonuclease H2 subunit A OS=Rattus norvegicus GN=Rnaseh2a PE=2 SV=1
266.0 [0..51] [302..16]
gi|39978149, gi|... - gi|39978149|ref|XP_370462.1| hypothetical protein MG06959.4 [Magnaporthe grisea 70-15], gb|EAA55302....
263.0 [0..19] [322..8]
RNH2A_MOUSE - Ribonuclease H2 subunit A OS=Mus musculus GN=Rnaseh2a PE=1 SV=2
260.0 [0..51] [304..16]
gi|68469222, gi|... - gi|77022682|ref|XP_888785.1| hypothetical protein CaO19_6562 [Candida albicans SC5314], gi|68470247|...
gi|76573598 - gi|76573598|dbj|BAE44682.1| hypothetical protein [Candida albicans]
259.0 [0..11] [320..87]
rnh-2 - status:Confirmed UniProt:Q9U6P6 protein_id:CAC70103.1
257.0 [0..44] [323..2]
CG13690-PA - This gene is referred to in FlyBase by the symbol Dmel\CG13690 (CG13690, FBgn0031252). It is a prote...
gi|220951678 - gi|220951678|gb|ACL88382.1| CG13690-PA [synthetic construct]
257.0 [0..1] [310..1]
gi|45361019, gi|... - gi|45361019|ref|NP_989146.1| ribonuclease H2, large subunit [Xenopus (Silurana) tropicalis], gi|3849...
255.0 [0..47] [320..12]
gi|71051192 - gi|71051192|gb|AAH99334.1| Unknown (protein for MGC:116529) [Xenopus laevis]
255.0 [0..47] [320..12]

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Predicted Domain #1
Region A:
Residues: [1-326]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDDHDAWEP EELVSDNNSS ENELQEDQNS SITFLPPSVN KSNPAKSNYY HSTVTDDISK  60
   61 SQPYRLGVDE AGRGPVLGPM VYAVAYCPVD FDLTNYGFAD SKTLASLKRE ELLKLICNKS 120
  121 NELGKNVGWS TMSISARELA AGMLRYRNKY NLNLQAHDTT IDLIKKVYES GINVTEIYVD 180
  181 TVGPPISYQE KLQAHFPQAK VTVTKKADSL FPIVSLASIC AKVTRDIQLE CARESIRTEN 240
  241 WGSGYSSDAR TTEWLKVNVD KIFGWKGDIV RYSWKTAKDL LELPSKSQSS IEIDWHEDDD 300
  301 TPTLNFTQKK KPNPASRSWF GSEFYF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1uaxA
Description: Crystal structure of the ribonuclease H2 from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease H activity 8.30690368719529 bayes_pls_golite062009
ribonuclease activity 4.81599779544001 bayes_pls_golite062009
exoribonuclease activity 3.01417328311605 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.89077854960958 bayes_pls_golite062009
exonuclease activity 2.86892175148145 bayes_pls_golite062009
nuclease activity 2.84202779131927 bayes_pls_golite062009
hydrolase activity 2.78602644579272 bayes_pls_golite062009
DNA polymerase activity 2.75375255857158 bayes_pls_golite062009
DNA-directed DNA polymerase activity 2.66279543366449 bayes_pls_golite062009
endonuclease activity 2.63074055051349 bayes_pls_golite062009
endoribonuclease activity 2.59247838057313 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.57498413015114 bayes_pls_golite062009
3'-5'-exoribonuclease activity 2.49957333962564 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.94077739152313 bayes_pls_golite062009
deoxyribonuclease activity 1.87431870698721 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
nucleotidyltransferase activity 1.12401205867904 bayes_pls_golite062009
nucleic acid binding 1.12235348738959 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
3'-5' exonuclease activity 0.86862629020506 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.782108781904855 bayes_pls_golite062009
exodeoxyribonuclease activity 0.77421125364834 bayes_pls_golite062009
binding 0.762139256580538 bayes_pls_golite062009
DNA binding 0.710663468386339 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.708753843279937 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.598360955770972 bayes_pls_golite062009
endodeoxyribonuclease activity 0.48776342704945 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle