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Protein Overview: rec8

General Information:
Name(s) found: rec8 / SPBC29A10.14 [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • meiotic cohesin complex subunit Rec8 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 561 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    inner kinetochore of condensed chromosome [IDALink to PubMed article]
    nuclear chromosome [ICLink to PubMed article]
    cohesin complex [IDALink to PubMed article]
    meiotic cohesin complex [IDALink to PubMed article]
    Biological Process: attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation [IMPLink to PubMed articleLink to PubMed article]
    linear element assembly [IMPLink to PubMed article]
    reciprocal meiotic recombination [IMPLink to PubMed article]
    meiotic sister chromatid segregation [IDALink to PubMed article][IMPLink to PubMed article]
    homologous chromosome segregation [IDALink to PubMed article]
    meiotic DNA double-strand break formation [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYNQDVLTK EKGGMGVIWL AATLGSKHSL RKLHKKDIMS VDIDEACDFV AFSPEPLALR  60
   61 LSSNLMIGVT RVWAHQYSFF HSQVSTLHLR VRKELDHFTS KPFKNIDIQN EQTNPKQLLL 120
  121 AEDPAFIPEV SLYDAFNLPS VDLHVDMSSF TQPKENPNIS VLETLPDSTS YLINTSQNYS 180
  181 LRNNVSSFVY EDSRAFSTEE PLDFEFDENG DIQELTKGTI NSDPSLQAAS QHSNLGSVQR 240
  241 EYNSEEQESR IHMFEIDEDV LPLPVPLQSV MDSEHNENEP RALKRRKVQK LLEPDENIEL 300
  301 STRTLSQWRK NYVERMIALE ATKYVRRRGA SSAKKKELNK FFDWESFHPL LKPWIEKLKP 360
  361 SNNTPSEIDD VLRNIDTSEV EVGRDVQGEL GLNIPWNTSS RSNSAINSKS HSQTGSEHST 420
  421 PLLDTKYRKR LPHSPSMPSR VEFLPALESS QFHETLNSEL SLQLSDDFVL YKNTQEENAH 480
  481 LMLSMEKECA NFYEYAKTAI YENNGRITFS SLLPNDLKRP VVAQAFSHLL SLATKSAFLV 540
  541 KQDKPYSEIS VSLNLKSTDA I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] Pfam 57.958607 No description for PF04825.4 was found. No confident structure predictions are available.
    2 View Details [126..199] deduced N/A No confident structure predictions are available.
    3 View Details [200..414] MSA 1.090988 View MSA. No confident structure predictions are available.
    4 View Details [415..561] PSI-BLAST 11.69897 Sc Smc1hd:Scc1-C complex, ATPgS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  3.74762577068811 bayes_pls_golite062009
  • DNA binding
    		•  3.6691593040775 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.56696430931691 bayes_pls_golite062009
  • binding
    		•  3.33026160538031 bayes_pls_golite062009
  • transcription factor activity
    		•  2.86565145658031 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.56454590328755 bayes_pls_golite062009
  • transcription activator activity
    		•  1.36544833032097 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.22911517186886 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.913018999939773 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.71350728967175 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.697234220778482 bayes_pls_golite062009
  • protein binding
    		•  0.653872239015235 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.300899564141452 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle