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Protein Overview: ura2

General Information:
Name(s) found: ura2 / SPAC16.03c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • dihydroorotase Ura2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 337 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: pyrimidine nucleotide biosynthetic process [ISSLink to PubMed article]
    pyrimidine base biosynthetic process [IEA]
    Molecular Function: zinc ion binding [IEA]
    dihydroorotase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKIPGLAD MHVHLRQDNM LKAVVPTVAE GGVSVAYVMP NLIPPITTVD ACLQYKKEIE  60
   61 QLDSKTTYLM SLYLSPETTP EVIYEAAKKG IRGVKSYPKG ATTNSESGVE SYEPFYPTFA 120
  121 AMQETGMILN IHGEVPPSKD NTVFTAEPKF LPTLLDLHQR FPKLKIVLEH CTTADAVEAV 180
  181 KACGESVAGT ITAHHLYLTQ KDWQDDPYCF CKPVAKTERD RRALIEAATS KNPKFFFGSD 240
  241 SAPHPRSSKL KTPPAAGVFT QPFAASYLAE VFDKEGRLDA LKDFACIFGR KFYCIPLDFK 300
  301 ESNIVLKKES FRVPESVAND LVPFHPNEVL QWHCSWE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 62.045757 Dihydroorotase from Escherichia coli: Loop Movement and Cooperativity between subunits

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • dihydroorotase activity
    		•  2.32070383330692 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  2.20489529944693 bayes_pls_golite062009
  • deaminase activity
    		•  1.79186203771221 bayes_pls_golite062009
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.60895003474033 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.629962267754185 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.573107361273483 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.506159010274668 bayes_pls_golite062009
  • DNA binding
    		•  0.462348875991261 bayes_pls_golite062009
  • binding
    		•  0.459041534336076 bayes_pls_golite062009
  • hydrolase activity
    		•  0.24275130580417 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle