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Protein Overview: pyp1

General Information:
Name(s) found: pyp1 / SPAC26F1.10c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • tyrosine phosphatase Pyp1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 550 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: protein amino acid dephosphorylation [IGILink to PubMed article]
    negative regulation of mitotic cell cycle [IMPLink to PubMed article]
    negative regulation of stress-activated MAPK cascade [TASLink to PubMed article]
    negative regulation of transcription by glucose [IMPLink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFSNGSKSS TFTIAPSGSC IALPPQRGVA TSKYAVHASC LQEYLDKEAW KDDTLIIDLR  60
   61 PVSEFSKSRI KGSVNLSLPA TLIKRPAFSV ARIISNLHDV DDKRDFQNWQ EFSSILVCVP 120
  121 AWIANYVTNA EVIGEKFRKE SYSGDFGILD LDYSKVSGKY PSVIDNSPVK SKLGALPSAR 180
  181 PRLSYSAAQT APISLSSEGS DYFSRPPPTP NVAGLSLNNF FCPLPENKDN KSSPFGSATV 240
  241 QTPCLHSVPD AFTNPDVATL YQKFLRLQSL EHQRLVSCSD RNSQWSTVDS LSNTSYKKNR 300
  301 YTDIVPYNCT RVHLKRTSPS ELDYINASFI KTETSNYIAC QGSISRSISD FWHMVWDNVE 360
  361 NIGTIVMLGS LFEAGREMCT AYWPSNGIGD KQVYGDYCVK QISEENVDNS RFILRKFEIQ 420
  421 NANFPSVKKV HHYQYPNWSD CNSPENVKSM VEFLKYVNNS HGSGNTIVHC SAGVGRTGTF 480
  481 IVLDTILRFP ESKLSGFNPS VADSSDVVFQ LVDHIRKQRM KMVQTFTQFK YVYDLIDSLQ 540
  541 KSQVHFPVLT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 18.69897 Erk2 binding domain of Mapk phosphatase mkp-3
    2 View Details [89..550] PSI-BLAST 63.69897 Crystal structure of human tyrosine phosphatase SHP-1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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