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View Structure Prediction Details

Protein: pyp1
Organism: Schizosaccharomyces pombe
Length: 550 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pyp1.

Description E-value Query
Range
Subject
Range
gi|17225445, gi|... - gi|62177150|ref|NP_001014310.1| protein tyrosine phosphatase, receptor type, D isoform A [Mus muscul...
332.0 [0..78] [549..484]
gi|109111546 - gi|109111546|ref|XP_001112074.1| PREDICTED: protein tyrosine phosphatase, receptor type, D isoform 1...
331.0 [0..78] [549..731]
gi|18860894 - gi|18860894|ref|NP_569077.1| protein tyrosine phosphatase, receptor type, D isoform 4 precursor [Hom...
330.0 [0..78] [549..731]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFSNGSKSS TFTIAPSGSC IALPPQRGVA TSKYAVHASC LQEYLDKEAW KDDTLIIDLR  60
   61 PVSEFSKSRI KGSVNLSLPA TLIKRPAF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.69897
Match: 1hzmA
Description: Erk2 binding domain of Mapk phosphatase mkp-3
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [89-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVARIISNLH DVDDKRDFQN WQEFSSILVC VPAWIANYVT NAEVIGEKFR KESYSGDFGI  60
   61 LDLDYSKVSG KYPSVIDNSP VKSKLGALPS ARPRLSYSAA QTAPISLSSE GSDYFSRPPP 120
  121 TPNVAGLSLN NFFCPLPENK DNKSSPFGSA TVQTPCLHSV PDAFTNPDVA TLYQKFLRLQ 180
  181 SLEHQRLVSC SDRNSQWSTV DSLSNTSYKK NRYTDIVPYN CTRVHLKRTS PSELDYINAS 240
  241 FIKTETSNYI ACQGSISRSI SDFWHMVWDN VENIGTIVML GSLFEAGREM CTAYWPSNGI 300
  301 GDKQVYGDYC VKQISEENVD NSRFILRKFE IQNANFPSVK KVHHYQYPNW SDCNSPENVK 360
  361 SMVEFLKYVN NSHGSGNTIV HCSAGVGRTG TFIVLDTILR FPESKLSGFN PSVADSSDVV 420
  421 FQLVDHIRKQ RMKMVQTFTQ FKYVYDLIDS LQKSQVHFPV LT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.69897
Match: 2b3oA
Description: Crystal structure of human tyrosine phosphatase SHP-1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle