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Protein Overview: ade4

General Information:
Name(s) found: ade4 / SPAC4D7.08c [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • amidophosphoribosyltransferase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 533 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][ISSLink to PubMed article]
    Biological Process: purine nucleotide biosynthetic process [TASLink to PubMed article]
    'de novo' IMP biosynthetic process [ISSLink to PubMed article]
    nucleoside metabolic process [IEA]
    purine base biosynthetic process [ICLink to PubMed article]
    Molecular Function: magnesium ion binding [IEA]
    amidophosphoribosyltransferase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGILALMLA DPHQQACPEI YEGLYSLQHR GQDAAGIVTA GNKGRLYQCK GSGMVADVFS  60
   61 QHQLRQLVGS MGIGHLRYPT AGSCAHSEAQ PFYVNSPYGL VLGHNGNLIN GPELRRFLDT 120
  121 EAHRHVNTGS DSELLLNIFA YELQRLDKFR INENDIFEAL RNVYDRVNGG YACVAMIAGL 180
  181 GVLGFRDPNG IRPLVIGERD TPEGKDYMLA SESVVLTQFG YRTFRDIRPG ECVFIRRSNR 240
  241 EDILAGFRGP RLFSRQILPC LRFTPDIFEY VYFARPDSVI DGLSVYQSRL NMGEKLAHTI 300
  301 MKRFGPDYME KIDAVIPVPD SARTSALALA QTAQLPYVEA FIKNRYIGRT FIMPGQQIRR 360
  361 KSVRRKLNVQ PQEFFDKNVL IVDDSIVRGT TSREIVQMAR ESGAKNVYLA SCAPMITHPH 420
  421 VYGIDLADCK DLIAYGKTED EVAEAISADG VIYQTLEDLL DSCRTAELTE FEVGLFTGEY 480
  481 TTGASKEYLV HLEQMRIANN RARKHSFAED EEREAPEDIS LHNTHSDVTF DFV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..533] PSI-BLAST 113.0 Glutamine PRPP amidotransferase, C-terminal domain; Glutamine PRPP amidotransferase, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uracil phosphoribosyltransferase activity
    		•  2.36237864658341 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  1.51875493459374 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • adenine phosphoribosyltransferase activity
    		•  0.985266832225609 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  0.625087274084001 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.283725923623827 bayes_pls_golite062009
  • ligase activity
    		•  0.204093345072151 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.0940838340168359 bayes_pls_golite062009
  • peptidase activity
    		•  0.0898497842822991 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.057753538747651 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.012663147802059 bayes_pls_golite062009
  • protein binding
    		•  0.00621436730716318 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.54

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle