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Protein Overview: pfh1

General Information:
Name(s) found: pfh1 / SPBC887.14c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • pif1 helicase homolog Pfh1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 805 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    G2 phase of mitotic cell cycle [IMPLink to PubMed article]
    DNA-dependent DNA replication [TASLink to PubMed article]
    DNA recombination [ISSLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    DNA replication, removal of RNA primer [IGILink to PubMed article]
    DNA replication, Okazaki fragment processing [IGILink to PubMed article]
    mitochondrial genome maintenance [IMPLink to PubMed article]
    Molecular Function: ATP binding [ISSLink to PubMed article]
    DNA binding [IEA]
    ATP-dependent 5'-3' DNA helicase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSCQSLYKF SHSFRKRIPV MFQRAQQKSS LLHTQNESSH QPSLNKLGGF SSASLNFNSS  60
   61 RSSTNDDQQT FSSQSDNLPS SPITLPAKRG RSAASLKQLD NTVGFDVSKP SLPVFENSGL 120
  121 GSKYSTEIAN GVYIDENDFD DDLLLENDID QKPIPWSSSP IEHTKLTKSM LSSEKRSKNH 180
  181 LSKIYEDHTS EKGASSVISS NITRQGIKRS RTLPWAVDPY RYGDPDPKRT STSADISQHT 240
  241 VSNDSSNKLS NGRSSSLDSL AKKRMSKSKS TPQISKKFSV PLNSASKSPI GSSLFKTSDS 300
  301 RKKSVPSIFL SDEQKRILDM VVEQQHSIFF TGSAGTGKSV LLRKIIEVLK SKYRKQSDRV 360
  361 AVTASTGLAA CNIGGVTLHS FAGVGLARES VDLLVSKIKK NKKCVNRWLR TRVLIIDEVS 420
  421 MVDAELMDKL EEVARVIRKD SKPFGGIQLV LTGDFFQLPP VPENGKESKF CFESQTWKSA 480
  481 LDFTIGLTHV FRQKDEEFVK MLNELRLGKL SDESVRKFKV LNRTIEYEDG LLPTELFPTR 540
  541 YEVERSNDMR MQQINQNPVT FTAIDSGTVR DKEFRDRLLQ GCMAPATLVL KVNAQVMLIK 600
  601 NIDDQLVNGS LGKVIGFIDD ETYQMEKKDA EMQGRNAFEY DSLDISPFDL PDVKQKKYKL 660
  661 IAMRKASSTA IKWPLVRFKL PNGGERTIVV QRETWNIELP NGEVQASRSQ IPLILAYAIS 720
  721 IHKAQGQTLD RVKVDLGRVF EKGQAYVALS RATTQEGLQV LNFSPAKVMA HPKVVQFYKQ 780
  781 LASVNGLPIR NENKAPVQMR GVKNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..119] deduced N/A No confident structure predictions are available.
    2 View Details [120..164] PSI-BLAST 44.221849 No description for 2gjkA was found.
    3 View Details [165..698] PSI-BLAST 28.221849 RecBCD:DNA complex
    4 View Details [699..805] PSI-BLAST 62.69897 No description for 2is1A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.44689197844883 bayes_pls_golite062009
  • hydrolase activity
    		•  2.18454736627863 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.81138802583782 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.54436515966471 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.51134988628578 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.49633029954726 bayes_pls_golite062009
  • microtubule motor activity
    		•  1.35938517416356 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.2539059700735 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • motor activity
    		•  1.14667913749579 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.117585097627 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.989226939888218 bayes_pls_golite062009
  • DNA binding
    		•  0.967303417236485 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.712344060953362 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.62080146588728 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.568457189190858 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.500462538667228 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.31144582840038 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.18426050934025 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.14606996093053 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.13050483816765 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0434163635422169 bayes_pls_golite062009
  • actin binding
    		•  0.00482938540552702 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.95561462330096E-4 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle