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Protein Overview: pdb1

General Information:
Name(s) found: pdb1 / SPBC30D10.13c [Sanger Pombe]
Description(s) found:
Found 22 descriptions.
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  • pyruvate dehydrogenase e1 component beta subunit Pdb1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 366 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial pyruvate dehydrogenase complex [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: acetyl-CoA biosynthetic process from pyruvate [ISSLink to PubMed article]
    Molecular Function: pyruvate dehydrogenase (acetyl-transferring) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRLQKFGEI VGTSRSWKLL SSTIAKRYSS SSNGVKEMTV RDALNSAMEE EMKRDDRVFL  60
   61 IGEEVAQYNG AYKISRGLLD KFGPKRVIDT PITEMGFTGL ATGAAFAGLR PICEFMTFNF 120
  121 SMQAIDHIVN SAARTLYMSG GIQACPIVFR GPNGPAAAVA AQHSQHFAPW YGSIPGLKVV 180
  181 SPYSAEDARG LLKAAIRDPN PVVVLENEIL YGKTFPISKE ALSEDFVLPF GLAKVERPGK 240
  241 DITIVGESIS VVTALEAADK LKADYGVEAE VINLRSIRPL DINTIAASVK KTNRIVTVDQ 300
  301 AYSQHGIGSE IAAQIMESDA FDYLDAPVER VSMADVPMPY SHPVEAASVP NADVVVAAAK 360
  361 KCLYIK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..366] PSI-BLAST 85.30103 E1-beta subunit of pyruvate dehydrogenase, Pyr module; E1-beta subunit of pyruvate dehydrogenase, C-domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyruvate dehydrogenase activity
    		•  11.3856674722026 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  11.0549577473177 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  10.8180381281695 bayes_pls_golite062009
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    		•  7.00951713446616 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.65146926050423 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  4.51986503762195 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  2.61614462349133 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  1.29819462996182 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.667418924427388 bayes_pls_golite062009
  • binding
    		•  0.551586872853971 bayes_pls_golite062009
  • catalytic activity
    		•  0.545407789079971 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.281475773435032 bayes_pls_golite062009
  • pyruvate decarboxylase activity
    		•  0.198062360371269 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle