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Protein Overview: msp1

General Information:
Name(s) found: msp1 / SPBC1718.06 [Sanger Pombe]
Description(s) found:
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  • gi|7106063|emb|CAB75996.1| mitochondrial GTPase Msp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19113244|ref|NP_596452.1| mitochondrial GTPase Msp1 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|15214069|sp|P87320.2|MSP1_SCHPO RecName: Full=Protein msp1, mitochondrial; Flags: Precursor [NCBI NR]
  • pir||T50334 dynamin-related protein [imported] - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • mitochondrial GTPase Msp1 [Sanger Pombe]
  • Protein msp1, mitochondrial OS=Schizosaccharomyces pombe GN=msp1 PE=2 SV=2 [Swiss-Prot]
  • REQUIRED FOR MITOCHONDRIAL MAINTENANCE; HUMAN HOMOLOG OPA1IS MUTATED IN DOMINANT OPTIC ATROPHY; PUTATIVE DYNAMIN FAMILY OF GTPASES: P87320;Q9P7N8; [pompepVF.fasta]
  • PROTEIN REQUIRED FOR MITOCHONDRIAL MAINTENANCE; HUMAN HOMOLOGUE OPA1IS MUTATED IN DOMINANT OPTIC ATROPHY; PUTATIVE MEMBER OF THE DYNAMIN FAMILY OF GTPASES: P87320;Q9P7N8; [pompepV13]
  • Msp1 protein, mitochondrial precursor [pompep4896]
  • |msp1||required for mitochondrial DNA maintenance (PMID 9790976) [pompepnew.fasta]
  • |msp1||involved in mitochondrial genome maintenance (required) (PMID 9790976)|Schizosaccharomyces pombe|chr 2|||Manual [pombe041504.fasta]
  • dynamin-related protein [Schizosaccharomyces pombe]gi|7106063|emb|CAB75996.1| msp1 [Schizosaccharomyces pombe]gi|15214069|sp|P87320|MSP1_SCHPO Msp1 protein, mitochondrial precursorgi|11359051|pir||T50334 dynamin-related protein [imported] - fission yea [nrdb_11152004_Chlamydomonas]
  • |mgm1||GTPase|Schizosaccharomyces pombe|chr 2|||Manual [pompep2242005.fasta]
  • (P87320) Msp1 protein, mitochondrial precursor [pompep4896_normal_reversed]
  • |msp1|mgm1|mitochondrial GTPase Msp1|Schizosaccharomyces pombe|chr 2|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • Protein msp1, mitochondrial precursor [nr-271106-contam.fasta]
  • hypothetical protein SPBC1718.06 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPBC1718.06 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • |msp1|mgm1|mitochondrial dynamin family GTPase Msp1|Schizosaccharomyces pombe|chr 2|||Manual [Other_S_Pombe_12-15-2011_reversed.fasta]
  • Protein msp1, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=msp1 PE=3 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 903 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    fungal-type vacuole membrane [IDALink to PubMed article]
    integral to membrane [IEA]
    Biological Process: mitochondrial fusion [IGILink to PubMed article][IMPLink to PubMed article]
    mitochondrion organization [IMPLink to PubMed article]
    mitochondrial genome maintenance [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: GTP binding [ISSLink to PubMed article]
    protein binding [IPILink to PubMed article]
    GTPase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGISWFLSRF RIRTVAPSSF LKPRGLVYRP SQIRRRVSLL SLSGFHPYRA YSILGPKTPT  60
   61 AFNSANTVRF FSFSSISRLV FRSLRLPVAG FSLVAGGAAY IGAQVQRASD YTKDIFDKTF 120
  121 GILDSTWEKT RETVASVTNV QLPEISMPLW LEKILRLDEE SAERRRVLQA ERAKEHRSNS 180
  181 NDKQKSSDND EDPNDTTVGI GAALAASILS VDSVDGEDTL TADEKRKLAQ ESKEDRMMLF 240
  241 TKKMIEIRNI LQDIQDNNSA VTLPSIVVIG SQSSGKSSVL EAIVGHEFLP KGSNMVTRRP 300
  301 IELTLVHSAD TAIPYGEFSG VQLGKITDFS KIQHILTDLN MAVPSSQGVD DNPIRLTIYA 360
  361 SHIPNLSLID LPGYIQIHSE DQPADLDMKI SKLCEKYIRE PNIILAVCAA DVDLANSAAL 420
  421 RASRRVDPLG LRTIGVVTKM DLVPPSKAIS ILHNNNYPLH YGYIGVISRI VPTGRFSAGQ 480
  481 NLTDLVSTQE NSYFSTHQQF ADARIGNYLG IQSLRKCLIN VLEYTMSKNL QHTADSIRTE 540
  541 LEECNYQYKV QYNDRVLTAD SYIAEGLDIF KAAFKEFTQK FGKSEVRDLL KSSLNEKVMD 600
  601 LLAERYWTDD DISNWSKHTN ALDEHWKYKL DSCVSTLTRM GLGRVSTLLV TDSISKCIDE 660
  661 ITKASPFADH PAAMQYIMNA AQDILRRRFH ATSEQVENCV KPYKYDVEVN DDEWKSSRGQ 720
  721 AEKLLQRELG LCQSALEKIK NAVGSRRMNQ VLQYLEEQKT SSEPLPASYS TALLEQGRML 780
  781 QYLKMREDIL KLRISVLKSR ACKHKEAKYT CPEIFLNAVS DKLVNTAVLF INIELLSEFY 840
  841 YQFPRELDQR LIHSLSSEQL NAFVNENPRL KSQLQLQHKR QCLELALQKI NSLVILEQQA 900
  901 DSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] deduced N/A No confident structure predictions are available.
    2 View Details [220..554] PSI-BLAST 81.154902 Dynamin G domain
    3 View Details [555..756] MSA 1.20798 View MSA. No confident structure predictions are available.
    4 View Details [757..903] MSA 5.104995 View MSA. Confident ab initio structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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