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Protein Overview: met26

General Information:
Name(s) found: met26 / SPAC9.09 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • homocysteine methyltransferase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 764 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: methionine biosynthetic process [IMPLink to PubMed article]
    adenine biosynthetic process [IMPLink to PubMed article]
    cysteine metabolic process [RCALink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKSAVLGFP RIGKNRELKK ATEAYWSGKT SAEELLATAK QLRLEHWKLQ KAQGVDIIPS  60
   61 NDFSLYDQIM DHSFSFNVIP PRYRLSGLSS LDTYFAMGRG MQRAATADKA AVDVPAGEMV 120
  121 KWFDSNYHFL RPEVSEETDF KLSSTKALDE FLEAKEAGII TRPVLVGPVT YLFIAKAAKG 180
  181 SSIKPIELLP KLLPVYVELI KKLTEAGAEY IQIDEPILTL DLPQEILASY KEAYETLGKI 240
  241 GKLILTTYFG SLQSNADVLK GLPIAGVHVD VVRAPENLDR ALAVLGENQI ISVGVVSGRN 300
  301 IWKTDFQKAT AIIEKAISAV GSERVQVASS SSILHIPHSL SGEDQINPEI KRWFAFAVEK 360
  361 CAELAILTKA ANDGPASVRA ELEANAADCK ARAESPITNV EAVRERQSKV TPQMHERKSP 420
  421 FETRYAKQQA SLKLPLFPTT TIGSFPQTKE IRVTRNRFAK GLISQEEYDA FIRKEISDVV 480
  481 KFQEEVGLDV LVHGEPERND MVQYFGERME GFVFTVNGWV QSYGSRCVRP PIIVGDVYRP 540
  541 APMTVKESQY AQSITSKPMK GMLTAPITIL RWSFPRDDVH DSVQAQQIAL GLRDEVLDLE 600
  601 KAGIKVIQCD EPALREGLPL RRAEWDEYLK WAIDAFRLAT AAVQDDTQIH SHFCYSDFND 660
  661 IFDAIQRLDA DVVSIENSKS DMKLLNVLSR YTSCIGPGLF DIHSPRVPPV SEFKERIDAI 720
  721 VKHVPKDHLW LNPDCGLKTR GWPETTADLK NMIAAAREAR EQYA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..764] PSI-BLAST 1000.0 A. thaliana cobalamine independent methionine synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • uroporphyrinogen decarboxylase activity
    		•  3.13638443707338 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  3.0142199413027 bayes_pls_golite062009
  • catalytic activity
    		•  2.37862248560593 bayes_pls_golite062009
  • binding
    		•  1.590130518929 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.54242506764415 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.52150758949987 bayes_pls_golite062009
  • lyase activity
    		•  0.825209465219608 bayes_pls_golite062009
  • protein binding
    		•  0.21865699924356 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle