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Protein Overview: isp6

General Information:
Name(s) found: isp6 / SPAC4A8.04 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • vacuolar serine protease Isp6 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 467 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDALink to PubMed article]
    fungal-type vacuole [TASLink to PubMed article]
    Biological Process: vacuole organization [IMPLink to PubMed article]
    autophagy [IMPLink to PubMed article]
    conjugation with cellular fusion [IMPLink to PubMed article]
    regulation of nitrogen compound metabolic process [IMPLink to PubMed article]
    proteolysis involved in cellular protein catabolic process [IMPLink to PubMed article]
    RNA catabolic process [IGILink to PubMed article]
    cellular response to nitrogen starvation [IEPLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: serine-type peptidase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIPYSNLFS AAAGLALFAS TACAAPVMPA TDSDIAHAGI RPELDNAFYD SHGEAATPKH  60
   61 KPHAGPNAAP LLSASNADTT GLDSHYIIVL QPDLSEQEFQ AHTNWVSEMH QMDIASQEDE 120
  121 YYDTSDSNYM FGLKHVYDFG EDSFKGYSGQ FSSNIVEQIR LHPHVIAVER DQVVSIKKLE 180
  181 TQSGAPWGLA RISHKSVKYD DIGKYVYDSS AGDNITAYVV DTGVSIHHVE FEGRASWGAT 240
  241 IPSGDVDEDN NGHGTHVAGT IASRAYGVAK KAEIVAVKVL RSSGSGTMAD VIAGVEWTVR 300
  301 HHKSSGKKTS VGNMSLGGGN SFVLDMAVDS AVTNGVIYAV AAGNEYDDAC YSSPAASKKA 360
  361 ITVGASTIND QMAYFSNYGS CVDIFAPGLN ILSTWIGSNT STNTISGTSM ATPHVAGLSA 420
  421 YYLGLHPAAS ASEVKDAIIK MGIHDVLLSI PVGSSTINLL AFNGAQE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] deduced N/A No confident structure predictions are available.
    2 View Details [70..190] PSI-BLAST 3.69897 Subtilisin prosegment
    3 View Details [191..467] PSI-BLAST 47.30103 Proteinase K

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • peptidase activity
    		•  4.68838733699853 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.20928698248021 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.45296270246929 bayes_pls_golite062009
  • hydrolase activity
    		•  3.36483239319728 bayes_pls_golite062009
  • serine hydrolase activity
    		•  1.90036575189745 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  1.89198766955068 bayes_pls_golite062009
  • binding
    		•  1.85875472341221 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  1.23150012549143 bayes_pls_golite062009
  • catalytic activity
    		•  0.597535457699629 bayes_pls_golite062009
  • protein binding
    		•  0.380935140681308 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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