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Protein Overview: tif51

General Information:
Name(s) found: tif51 / SPAC26H5.10c [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • translation initiation factor eIF5A [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 157 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytosolic ribosome [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: positive regulation of translational termination [ISS]
    translational frameshifting [ISS]
    positive regulation of translational elongation [ISSLink to PubMed article]
    peptidyl-lysine modification to hypusine [IEA]
    Molecular Function: RNA binding [ISS]
    translation elongation factor activity [ISSLink to PubMed article]
    ribosome binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEEEHVDFE GGEAGASLTF PMQCSALRKN GHVVIKGRPC KIVDMSTSKT GKHGHAKVHI  60
   61 VALDIFNGRK YEDMSPSTHN MDVPVVKRDE YQLVNIDDGY LNLMTTDGTT KDDVRLPEGE 120
  121 LGNEIEEGFD EGRDLIITVV SAMGEETALA CRDAPSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run dam1 No Comments Liu X, et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] PSI-BLAST 38.154902 Structural Analysis of Leishmania mexicana eukaryotic initiation factor 5a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • U6 snRNA binding
    		•  7.69488393698619 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  6.60650180781768 bayes_pls_golite062009
  • structural molecule activity
    		•  6.0174879876147 bayes_pls_golite062009
  • translation initiation factor activity
    		•  5.09596850944863 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.89165617439497 bayes_pls_golite062009
  • translation elongation factor activity
    		•  3.58178742491041 bayes_pls_golite062009
  • DNA binding
    		•  3.38561002225202 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • RNA binding
    		•  1.76502371106766 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.74890841494748 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.69669059514663 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.54386990150255 bayes_pls_golite062009
  • translation regulator activity
    		•  1.46320772716954 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.40718318783582 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.38349489974693 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • transcription activator activity
    		•  0.990244702925461 bayes_pls_golite062009
  • mRNA binding
    		•  0.883475899526061 bayes_pls_golite062009
  • transcription factor activity
    		•  0.859071050218437 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.594907498313479 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.474251377131502 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.47336621289748 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.47336621289748 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.39251242706379 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.39251242706379 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.35186207828037 bayes_pls_golite062009
  • nuclease activity
    		•  0.26446253803519 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle