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Protein Overview: cpc2

General Information:
Name(s) found: cpc2 / SPAC6B12.15 [Sanger Pombe]
Description(s) found:
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  • gi|3023853|sp|Q10281.3|GBLP_SCHPO RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein; AltName: Full=Receptor of activated protein kinase C [NCBI NR]
  • gi|2440194|emb|CAB11079.1| RACK1 ortholog Cpc2 [Schizosaccharomyces pombe] [NCBI NR]
  • gi|19114682|ref|NP_593770.1| RACK1 homologue Cpc2 [Schizosaccharomyces pombe] [NCBI NR]
  • pir||T43299 probable GTP-binding regulatory protein beta chain - fission yeast (Schizosaccharomyces pombe) [NCBI NR]
  • RACK1 homologue Cpc2 [Sanger Pombe]
  • Guanine nucleotide-binding protein subunit beta-like protein OS=Schizosaccharomyces pombe GN=rkp1 PE=1 SV=3 [Swiss-Prot]
  • GUANINE NUCLEOTIDE REGULATORY PROTEIN; WD REPEAT PROTEIN; PHOSPHORYLATED BY RAN1P; REQUIRED FOR NORMAL MATING AND SPORULATION; INVOLVED IN ACTIN CYTOSKELETON ORGANIZATION THROUGH PROTEIN KINASE C-PCK2-SIGNALING: P78896;Q10281; [pompepVF.fasta]
  • GUANINE NUCLEOTIDE REGULATORY PROTEIN; WD REPEAT PROTEIN; PHOSPHORYLATED BY RAN1P; REQUIRED FOR NORMAL MATING AND SPORULATION; INVOLVED IN ACTIN CYTOSKELETON ORGANIZATION THROUGH PROTEIN KINASE C-PCK2-SIGNALING: AAK38633;P78896;Q10281; [pompepV13]
  • Guanine nucleotide-binding protein beta subunit-like protein (Receptor of activated protein kinase C) [pompep4896]
  • |cpc2|rkp1|guanine nucleotide regulatory protein [pompepnew.fasta]
  • |cpc2|rkp1|WD repeat protein|Schizosaccharomyces pombe|chr 1|||Manual [pombe041504.fasta]
  • WD repeat protein; RACK1 family (PMID 12688536); phosphorylated by Ran1p; involved in conjugation (regulation); involved in sporulation (regulation); involved in actin cytoskeletal organization (regulation) (PMID 11263963); involved in translation (regula [nrdb_11152004_Chlamydomonas]
  • (Q10281) Guanine nucleotide-binding protein beta subunit-like protein (Receptor of activated protein kinase C) [pompep4896_normal_reversed]
  • |cpc2|rkp1|RACK1 ortholog Cpc2|Schizosaccharomyces pombe|chr 1|||Manual [SGD_S-Pombe_na_10-23-2009_con_reversed.fasta]
  • hypothetical protein SPAC6B12.15 [Schizosaccharomyces pombe 972h-] [nr-271106-contam.fasta]
  • SPAC6B12.15 [Schizosaccharomyces pombe] [nr-271106-contam.fasta]
  • Guanine nucleotide-binding protein subunit beta-like protein (Receptor of activated protein kinase C) [nr-271106-contam.fasta]
  • |cpc2|rkp1|RACK1 homologue Cpc2|Schizosaccharomyces pombe|chr 1|||Manual [spombe-190209-contam.fasta]
  • Guanine nucleotide-binding protein subunit beta-like protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rkp1 PE=1 SV=3 [uniprot_sprot.fasta.20160308]
    • Organism: Schizosaccharomyces pombe
    Length: 314 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    Biological Process: regulation of actin cytoskeleton organization [IGILink to PubMed article]
    positive regulation of conjugation with cellular fusion [IMPLink to PubMed article]
    negative regulation of translation [ISS]
    regulation of fungal-type cell wall biogenesis [IGILink to PubMed article]
    cellular protein localization [IGILink to PubMed article]
    regulation of conjugation with cellular fusion [IGILink to PubMed article]
    Molecular Function: protein kinase C binding [IPILink to PubMed article]
    protein binding [IPILink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    ribosome binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEQLVLRAT LEGHSGWVTS LSTAPENPDI LLSGSRDKSI ILWNLVRDDV NYGVAQRRLT  60
   61 GHSHFVSDCA LSFDSHYALS ASWDKTIRLW DLEKGECTHQ FVGHTSDVLS VSISPDNRQV 120
  121 VSGSRDKTIK IWNIIGNCKY TITDGGHSDW VSCVRFSPNP DNLTFVSAGW DKAVKVWDLE 180
  181 TFSLRTSHYG HTGYVSAVTI SPDGSLCASG GRDGTLMLWD LNESTHLYSL EAKANINALV 240
  241 FSPNRYWLCA ATGSSIRIFD LETQEKVDEL TVDFVGVGKK SSEPECISLT WSPDGQTLFS 300
  301 GWTDNLIRVW QVTK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..314] PSI-BLAST 61.39794 Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle