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Protein Overview: esc1

General Information:
Name(s) found: esc1 / SPAC56F8.16 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • transcription factor Esc1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 413 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][NASLink to PubMed article]
    Biological Process: induction of conjugation upon nitrogen starvation [IMPLink to PubMed article]
    positive regulation of transcription, DNA-dependent [IMPLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: DNA binding [ISSLink to PubMed article]
    transcription factor activity [TASLink to PubMed article]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSYALPSMQ PTPTSSIPLR QMSQPTTSAP SNSASSTPYS PQQVPLTHNS YPLSTPSSFQ  60
   61 HGQTRLPPIN CLAEPFNRPQ PWHSNSAAPA SSSPTSATLS TAAHPVHTNA AQVAGSSSSY 120
  121 VYSVPPTNST TSQASAKHSA VPHRSSQFQS TTLTPSTTDS SSTDVSSSDS VSTSASSSNA 180
  181 SNTVSVTSPA SSSATPLPNQ PSQQQFLVSK NDAFTTFVHS VHNTPMQQSM YVPQQQTSHS 240
  241 SGASYQNESA NPPVQSPMQY SYSQGQPFSY PQHKNQSFSA SPIDPSMSYV YRAPESFSSI 300
  301 NANVPYGRNE YLRRVTSLVP NQPEYTGPYT RNPELRTSHK LAERKRRKEI KELFDDLKDA 360
  361 LPLDKSTKSS KWGLLTRAIQ YIEQLKSEQV ALEAYVKSLE ENMQSNKEVT KGT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] MSA 5.133997 View MSA. No confident structure predictions are available.
    2 View Details [191..269] deduced N/A No confident structure predictions are available.
    3 View Details [270..413] PSI-BLAST 22.0 Myc prot-oncogene protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • transcription activator activity
    		•  3.87875547821718 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.42035985454056 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.58879320178546 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.48787404513864 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • sterol response element binding
    		•  1.35908389783271 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.05787100777909 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • promoter binding
    		•  0.94414084000081 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.82134057325852 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.801830750183111 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle