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Protein Overview: csl4

General Information:
Name(s) found: csl4 / SPCC1840.11 [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
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  • exosome subunit Csl4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 181 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic exosome (RNase complex) [ISSLink to PubMed article]
    nuclear exosome (RNase complex) [ISSLink to PubMed article]
    nucleus [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    nucleolus [ISSLink to PubMed article]
    Biological Process: rRNA processing [ISSLink to PubMed article]
    mRNA catabolic process [ISSLink to PubMed article]
    Molecular Function: 3'-5'-exoribonuclease activity [ISSLink to PubMed article]
    RNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLVLPGQVV ARGAPNGEGT VKRGDYIIST RTGIFDPEKN SVTYPRKVEE TAVLPNVGSI  60
   61 VLARVSRINA RQATVNISVV DDVCTKDEFQ GVIHVQDIRA TEKNKVKVQN SFRPGDIVRA 120
  121 LVISLGDGSS YFLTTARNDL GVIFAQSSET GEQMFPVDYQ HMQTKSGYTE MRKCAKPILD 180
  181 E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..181] PSI-BLAST 34.69897 No description for 2nn6I was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  7.42330864261751 bayes_pls_golite062009
  • exoribonuclease activity
    		•  6.76241588209982 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  6.73428326869965 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  5.13367897180134 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.51084463039261 bayes_pls_golite062009
  • structural molecule activity
    		•  4.29692945022158 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  3.51306349336452 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.194200758646 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  3.07263153665399 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.73968547121328 bayes_pls_golite062009
  • DNA binding
    		•  2.71213098011194 bayes_pls_golite062009
  • exonuclease activity
    		•  2.66053639652924 bayes_pls_golite062009
  • RNA binding
    		•  2.41160981373213 bayes_pls_golite062009
  • binding
    		•  2.24181355929217 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.81524862921454 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.62996999055328 bayes_pls_golite062009
    		• 1.5765009871268 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  1.35850109411274 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  1.35845277283398 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  1.35845277283398 bayes_pls_golite062009
  • exoribonuclease II activity
    		•  1.18248519339188 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.996884322431837 bayes_pls_golite062009
  • hydrolase activity
    		•  0.724860465280978 bayes_pls_golite062009
  • nuclease activity
    		•  0.57381531077345 bayes_pls_golite062009
  • mRNA binding
    		•  0.4162128308402 bayes_pls_golite062009
  • ligase activity
    		•  0.346041081217685 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.32084431704638 bayes_pls_golite062009
  • transcription factor activity
    		•  0.298729064067577 bayes_pls_golite062009
  • translation regulator activity
    		•  0.22908707234671 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.179682348023561 bayes_pls_golite062009
  • catalytic activity
    		•  0.161830442565647 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.151650064901878 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.150235510823939 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.11625379846973 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.0740938021136293 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.0740938021136293 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle