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Protein Overview: mcs2

General Information:
Name(s) found: mcs2 / SPBP16F5.02 [Sanger Pombe]
Description(s) found:
Found 20 descriptions.
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  • cyclin Mcs2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 322 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    holo TFIIH complex [ISSLink to PubMed article]
    Biological Process: regulation of cell cycle [IGILink to PubMed article]
    transcription initiation from RNA polymerase II promoter [ISS]
    regulation of cyclin-dependent protein kinase activity [NAS]
    negative regulation of phosphorylation [ICLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed articleLink to PubMed article]
    cyclin-dependent protein kinase inhibitor activity [IGILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSADKFRDST HYRDWIFTEE DLSKTRAKVN EKFTNIVRER MLEELSLQNK EASLEVLPPT  60
   61 LTVEEELELV NYYSFQLNAL SSALSLPTHI RSTAILFFKR FYLINSVMEY SPKIISFTSL 120
  121 FLATKCNDHY ISIEQFCKNM PKTTPEEVLE YEFNVCQSLK WDLYVWLPFR PLQGFLLDCQ 180
  181 TVLPKVAVEK FYECHDLSKK FLIETLHSDI YFLHSPSIIA LGAIYHTNPT ICLQYIEAKK 240
  241 IPELQPLIIS ISANLKATKK FKIEKKKAQD YGRKLYFCMN PLRNKSSALY LKRKAEEEST 300
  301 NNNKWAKKFS TSSNVLDKNP FE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..322] PSI-BLAST 35.0 STRUCTURE OF CYCLIN MCS2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  8.12427628405368 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  6.12919068656167 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  2.90083336559452 bayes_pls_golite062009
  • kinase regulator activity
    		•  2.84789294954357 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.795846725429 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.51688704722199 bayes_pls_golite062009
  • binding
    		•  2.4204867358489 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.00665312545368 bayes_pls_golite062009
  • DNA binding
    		•  1.6980508926231 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.63159454080484 bayes_pls_golite062009
  • protein binding
    		•  1.47106731485576 bayes_pls_golite062009
  • transcription factor activity
    		•  1.0145450763465 bayes_pls_golite062009
  • protein kinase activity
    		•  0.957590284872001 bayes_pls_golite062009
  • kinase activity
    		•  0.79567569649664 bayes_pls_golite062009
  • transcription factor binding
    		•  0.749278791251235 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.729629809946521 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.567809158275482 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.561985718866596 bayes_pls_golite062009
  • kinase binding
    		•  0.451409627821468 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.15005807834588 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.138191616709499 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0696060248241566 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle