YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: bir1

General Information:
Name(s) found: bir1 / SPCC962.02c [Sanger Pombe]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • survivin homolog [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 997 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    spindle midzone [IDALink to PubMed article]
    spindle [IDALink to PubMed article]
    condensed nuclear chromosome kinetochore [IDALink to PubMed article]
    chromosome passenger complex [TASLink to PubMed article]
    Biological Process: mitotic cell cycle spindle assembly checkpoint [IGILink to PubMed article]
    mitotic spindle elongation [IMPLink to PubMed article]
    chromosome condensation [IMPLink to PubMed articleLink to PubMed article]
    protein localization to kinetochore [IGILink to PubMed article]
    mitotic sister chromatid segregation [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    cytokinesis [IGILink to PubMed article]
    protein localization to nucleolar rDNA repeats [IGILink to PubMed article]
    cellular protein localization [IGILink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPITSSSKR RWNRFRREMC NYSKRLDTFQ KKKWPRAKPT PETLATVGFY YNPISESNSE  60
   61 ERLDNVTCYM CTKSFYDWED DDDPLKEHIT HSPSCPWAYI LSSKNNPNQN PQAAALTKCR 120
  121 EQTFVDKVWP YTNRPDYHCE PSVMAASGFV YNPTADAKDA AHCLYCDINL HDWEPDDDPY 180
  181 TEHKRRRADC VFFTWKDPNS LSPTKLSFLS TSNIDPEDLT EDNSILPVSP TRDSTKSHKT 240
  241 LNFSPSRKNN LNARPLTMSL YTNTSEEKDS QPTRAPQSPT KPVLLTAPRR KNKSPKKSKP 300
  301 AVFKPVKPIF SDEDEDDDDL TASQPFSKGI CNDSMQVAKK NFTEEIPLKE DEKDNELEHL 360
  361 VSPATSVHTT VSDITGHQSV TDESDEQNNC MSTPPKIEIE SKIEEEISVV SKSKEISSSV 420
  421 SSVGKEQNHT EKQVAIETPE QQKVEKEDEH LNLQGSFIEE STKQPISSKP STSSPDMTDA 480
  481 ATGGRVSSSS FRDKILQTNF SPRSTIDSFS NISKKRNSEE ANDENDETNL KIPIPEKKRK 540
  541 FQEVLQSKNI LVSSTEDSHE PVKVTEDSQT AIHVSKFEDL ENKSMESEQS LQLLSESEND 600
  601 DKPLIDLIPL LAIKRKDNLV SGVLEKGKST STSKTKFDTS IVDFIEKPKT EISEVLPEEK 660
  661 RKAICDESQT VRVSIDRGVT KTRDVSSPVS DEKSENVNHE EANSGHTVMN VHSSLDPQPI 720
  721 VQPNELESGS YLKDLPDRNV GNSEKVTFQE DDINSPKLQS KNNQTVEAVN TETSDKLQEK 780
  781 EANHELENIE KIEEKLTEVD KVSLSDAFPD QEIKNSRTSV QNGTRSVSKN TPEKETKVDK 840
  841 IDNVSKKDVE TSPGSCETSS AFAKTYAEKE VTSINLPSVR KPLDESYYDH SISPFDPLCQ 900
  901 SSFLAPQTPV KSKHALPLVE ANAPPWEPID FSSLLESPVP NPVEPNKLSE KELDMTVEQW 960
  961 IKFMYAKCAK EFEEACEEKI EWLLEEGKRA EEYIQNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] PSI-BLAST 33.69897 BIR domains of XIAP
    2 View Details [115..232] PSI-BLAST 6.522879 Anti-apoptotic protein survivin
    3 View Details [233..441] deduced N/A No confident structure predictions are available.
    4 View Details [442..526] deduced N/A No confident structure predictions are available.
    5 View Details [527..908] PSI-BLAST 11.09691 Heavy meromyosin subfragment
    6 View Details [909..997] PSI-BLAST 6.69897 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule binding
    		•  4.86535736353162 bayes_pls_golite062009
  • tubulin binding
    		•  4.84666941238345 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.62581200332375 bayes_pls_golite062009
  • caspase inhibitor activity
    		•  3.24749466882424 bayes_pls_golite062009
  • binding
    		•  2.82472291325192 bayes_pls_golite062009
  • cysteine-type endopeptidase inhibitor activity
    		•  2.41011324527293 bayes_pls_golite062009
  • protein binding
    		•  1.77755878794519 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.6845701774335 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.59597592754555 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.57363964496853 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.47775468027242 bayes_pls_golite062009
    2
    Term Confidence Notes
  • microtubule binding
    		•  4.86535736353162 bayes_pls_golite062009
  • tubulin binding
    		•  4.84666941238345 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.62581200332375 bayes_pls_golite062009
  • caspase inhibitor activity
    		•  3.24749466882424 bayes_pls_golite062009
  • binding
    		•  2.82472291325192 bayes_pls_golite062009
  • cysteine-type endopeptidase inhibitor activity
    		•  2.41011324527293 bayes_pls_golite062009
  • protein binding
    		•  1.77755878794519 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.6845701774335 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.59597592754555 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.57363964496853 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.47775468027242 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle