| Protein: | bir1 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 997 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bir1.
| Description | E-value | Query Range |
Subject Range |
|
|
300.0 | [0..3] | [431..150] |
|
|
299.0 | [0..2] | [431..164] |
|
|
299.0 | [0..2] | [431..164] |
|
|
297.0 | [0..2] | [431..164] |
|
Region A: Residues: [1-114] |
1 11 21 31 41 51
| | | | | |
1 MKPITSSSKR RWNRFRREMC NYSKRLDTFQ KKKWPRAKPT PETLATVGFY YNPISESNSE 60
61 ERLDNVTCYM CTKSFYDWED DDDPLKEHIT HSPSCPWAYI LSSKNNPNQN PQAA
|
| Detection Method: |  |
| Confidence: | 33.69897 |
| Match: | 1c9qA |
| Description: | BIR domains of XIAP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| microtubule binding | 4.86535736353162 | bayes_pls_golite062009 |
| tubulin binding | 4.84666941238345 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.62581200332375 | bayes_pls_golite062009 |
| caspase inhibitor activity | 3.24749466882424 | bayes_pls_golite062009 |
| binding | 2.82472291325192 | bayes_pls_golite062009 |
| cysteine-type endopeptidase inhibitor activity | 2.41011324527293 | bayes_pls_golite062009 |
| protein binding | 1.77755878794519 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.6845701774335 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.59597592754555 | bayes_pls_golite062009 |
| endopeptidase inhibitor activity | 0.57363964496853 | bayes_pls_golite062009 |
| peptidase inhibitor activity | 0.47775468027242 | bayes_pls_golite062009 |
|
Region A: Residues: [115-232] |
1 11 21 31 41 51
| | | | | |
1 ALTKCREQTF VDKVWPYTNR PDYHCEPSVM AASGFVYNPT ADAKDAAHCL YCDINLHDWE 60
61 PDDDPYTEHK RRRADCVFFT WKDPNSLSPT KLSFLSTSNI DPEDLTEDNS ILPVSPTR
|
| Detection Method: | |
| Confidence: | 6.522879 |
| Match: | 1f3hA |
| Description: | Anti-apoptotic protein survivin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| microtubule binding | 4.86535736353162 | bayes_pls_golite062009 |
| tubulin binding | 4.84666941238345 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.62581200332375 | bayes_pls_golite062009 |
| caspase inhibitor activity | 3.24749466882424 | bayes_pls_golite062009 |
| binding | 2.82472291325192 | bayes_pls_golite062009 |
| cysteine-type endopeptidase inhibitor activity | 2.41011324527293 | bayes_pls_golite062009 |
| protein binding | 1.77755878794519 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 0.6845701774335 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.59597592754555 | bayes_pls_golite062009 |
| endopeptidase inhibitor activity | 0.57363964496853 | bayes_pls_golite062009 |
| peptidase inhibitor activity | 0.47775468027242 | bayes_pls_golite062009 |
|
Region A: Residues: [233-441] |
1 11 21 31 41 51
| | | | | |
1 DSTKSHKTLN FSPSRKNNLN ARPLTMSLYT NTSEEKDSQP TRAPQSPTKP VLLTAPRRKN 60
61 KSPKKSKPAV FKPVKPIFSD EDEDDDDLTA SQPFSKGICN DSMQVAKKNF TEEIPLKEDE 120
121 KDNELEHLVS PATSVHTTVS DITGHQSVTD ESDEQNNCMS TPPKIEIESK IEEEISVVSK 180
181 SKEISSSVSS VGKEQNHTEK QVAIETPEQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [442-526] |
1 11 21 31 41 51
| | | | | |
1 QKVEKEDEHL NLQGSFIEES TKQPISSKPS TSSPDMTDAA TGGRVSSSSF RDKILQTNFS 60
61 PRSTIDSFSN ISKKRNSEEA NDEND
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [527-908] |
1 11 21 31 41 51
| | | | | |
1 ETNLKIPIPE KKRKFQEVLQ SKNILVSSTE DSHEPVKVTE DSQTAIHVSK FEDLENKSME 60
61 SEQSLQLLSE SENDDKPLID LIPLLAIKRK DNLVSGVLEK GKSTSTSKTK FDTSIVDFIE 120
121 KPKTEISEVL PEEKRKAICD ESQTVRVSID RGVTKTRDVS SPVSDEKSEN VNHEEANSGH 180
181 TVMNVHSSLD PQPIVQPNEL ESGSYLKDLP DRNVGNSEKV TFQEDDINSP KLQSKNNQTV 240
241 EAVNTETSDK LQEKEANHEL ENIEKIEEKL TEVDKVSLSD AFPDQEIKNS RTSVQNGTRS 300
301 VSKNTPEKET KVDKIDNVSK KDVETSPGSC ETSSAFAKTY AEKEVTSINL PSVRKPLDES 360
361 YYDHSISPFD PLCQSSFLAP QT
|
| Detection Method: | |
| Confidence: | 11.09691 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [909-997] |
1 11 21 31 41 51
| | | | | |
1 PVKSKHALPL VEANAPPWEP IDFSSLLESP VPNPVEPNKL SEKELDMTVE QWIKFMYAKC 60
61 AKEFEEACEE KIEWLLEEGK RAEEYIQNL
|
| Detection Method: | |
| Confidence: | 6.69897 |
| Match: | 1c1gA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
