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Protein Overview: ace2

General Information:
Name(s) found: ace2 / SPAC6G10.12c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • transcription factor Ace2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 533 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    [NOT]cytoplasm [IDALink to PubMed article]
    Biological Process: regulation of transcription, mitotic [IGILink to PubMed articleLink to PubMed article]
    cytokinetic cell separation [IMPLink to PubMed article]
    gene-specific transcription from RNA polymerase II promoter [RCALink to PubMed article]
    Molecular Function: transcription factor activity [ISSLink to PubMed article]
    zinc ion binding [IEA]
    specific RNA polymerase II transcription factor activity [RCALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSYLSSSS QKSFESFRQE ESPACNHSYQ RDYETFGDSK HTSFSSFAPF ENEVSLNQAV  60
   61 IPSPPSHLQN FQDQFDYSSV LKTPFNPLLE ANSAYFLSNQ ISLPDSHSYA SSFDASLSPP 120
  121 SSPLTCVSQI HTEQNFNNND AFSLTNSQQA FSEIGYDASN WIDELDSQQQ VLSFPEFDIP 180
  181 EIKTETCSNK DHLENFDYLS SSIPETSGPA SSVLPSSSQL ESFNEFMFLP SSPPGLDEIN 240
  241 GAPSFEELNF QISQPSPAHP VDLSSPETAP NISPVSPFAQ LVKLEPTSPQ KPSFALDSSF 300
  301 SHLDVCRHTD NQKAFAKLSS PAEYVSEFEK FSSVCDHGLD ISNANINNTL TQQFALSAPY 360
  361 ESCIVTKKPE PCITVKEEEQ LAPKIESADL SITPQVTEHD SKPPVRISYD HRCKTRKQST 420
  421 RICRIPPETM ASLYCGPEAD GKYVCLYNGC NKRIARKYNV ESHIQTHLSD RPYRCDLCKA 480
  481 GFVRHHDLKR HLRIHENGRP YVCECLKRFN RLDALNRHKQ RNICVGGVDR RQH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..160] deduced N/A No confident structure predictions are available.
    2 View Details [161..371] PSI-BLAST 29.39794 No description for 2i13A was found.
    3 View Details [372..533] PSI-BLAST 13.69897 Five-finger GLI1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.31369346002275 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.64349785387632 bayes_pls_golite062009
  • chromatin binding
    		•  1.53640935908107 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.0497955246512 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.10558148421807 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle