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Protein Overview: Myb-PE, Myb-PA, ...

General Information:
Name(s) found: Myb-PE / FBpp0089405 [FlyBase]
Myb-PC / FBpp0089404 [FlyBase]
Myb-PD / FBpp0089403 [FlyBase]
Myb-PB / FBpp0089402 [FlyBase]
Myb-PA / FBpp0073961 [FlyBase]
Description(s) found:
Found 69 descriptions.
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  • The gene Myb oncogene-like is referred to in FlyBase by the symbol Dmel\Myb (CG9045, FBgn0002914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15748865..15751854. It has the cytological map location 13F14. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; regulation of biological process; microtubule organizing center organization; microtubule cytoskeleton organization; cell proliferation; cell division; regulation of metabolic process; anatomical structure development; regulation of cellular component organization. 36 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: cell cycle; peripheral nervous system; organ system; adult segment; nervous system; cell cycle process; external compound sense organ; imaginal precursor; adult mesothoracic segment; thoracic segment. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Myb oncogene-like is referred to in FlyBase by the symbol Dmel\Myb (CG9045, FBgn0002914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15748865..15751854. It has the cytological map location 13F14. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; regulation of biological process; microtubule organizing center organization; microtubule cytoskeleton organization; cell proliferation; cell division; regulation of metabolic process; anatomical structure development; regulation of cellular component organization. 36 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: cell cycle; peripheral nervous system; organ system; adult segment; nervous system; cell cycle process; external compound sense organ; imaginal precursor; adult mesothoracic segment; thoracic segment. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Myb oncogene-like is referred to in FlyBase by the symbol Dmel\Myb (CG9045, FBgn0002914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15748865..15751854. It has the cytological map location 13F14. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; regulation of biological process; microtubule organizing center organization; microtubule cytoskeleton organization; cell proliferation; cell division; regulation of metabolic process; anatomical structure development; regulation of cellular component organization. 36 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: cell cycle; peripheral nervous system; organ system; adult segment; nervous system; cell cycle process; external compound sense organ; imaginal precursor; adult mesothoracic segment; thoracic segment. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Myb oncogene-like is referred to in FlyBase by the symbol Dmel\Myb (CG9045, FBgn0002914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15748865..15751854. It has the cytological map location 13F14. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; regulation of biological process; microtubule organizing center organization; microtubule cytoskeleton organization; cell proliferation; cell division; regulation of metabolic process; anatomical structure development; regulation of cellular component organization. 36 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: cell cycle; peripheral nervous system; organ system; adult segment; nervous system; cell cycle process; external compound sense organ; imaginal precursor; adult mesothoracic segment; thoracic segment. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Myb oncogene-like is referred to in FlyBase by the symbol Dmel\Myb (CG9045, FBgn0002914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:15748865..15751854. It has the cytological map location 13F14. There is experimental evidence that it has the molecular function</span>: DNA binding. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: cell cycle; cell cycle process; organelle organization; regulation of biological process; microtubule organizing center organization; microtubule cytoskeleton organization; cell proliferation; cell division; regulation of metabolic process; anatomical structure development; regulation of cellular component organization. 36 alleles are reported. The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: cell cycle; peripheral nervous system; organ system; adult segment; nervous system; cell cycle process; external compound sense organ; imaginal precursor; adult mesothoracic segment; thoracic segment. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 657 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    polytene chromosome [IDA]
    Myb complex [IDA]
    Biological Process: cell proliferation [IMP]
    spindle organization [IMP]
    centrosome cycle [IMP]
    regulation of mitosis [IGI][IMP]
    centriole replication [IMP]
    mitotic spindle organization [IMP]
    regulation of transcription, DNA-dependent [IDA]
    cytokinesis [IMP]
    mitosis [IMP]
    regulation of transcription [IEA][ISS]
    cell cycle [IGI][IMP]
    eggshell chorion gene amplification [IMP][TAS]
    centrosome organization [IMP]
    Molecular Function: DNA binding [IDA][ISS][NAS]
    transcription factor activity [TAS]
    transcription activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASASTENGE ELMNYGSNSD SEESEYSENE DTQVCDKDSQ QNSNADSGYP LDSPELQDSK  60
   61 TTGQKGQNKS GKTSIGAVHP NYGFGKRWSK SEDVLLKQLV ETHGENWEII GPHFKDRLEQ 120
  121 QVQQRWAKVL NPELIKGPWT RDEDDMVIKL VRNFGPKKWT LIARYLNGRI GKQCRERWHN 180
  181 HLNPNIKKTA WTEKEDEIIY QAHLELGNQW AKIAKRLPGR TDNAIKNHWN STMRRKYDVE 240
  241 RRSVNASGSD LKSSRTHLIT LIKSGGISKC MNNMQHNKES GGEAVNKSEN ADGASVTAVK 300
  301 GGDLAQESQD DHQKGSNLAH LSMQHLIKLT MPRQTPIILK RTRKHIPETH HQAGCSSSET 360
  361 FNQEEAAGNA RSRPPSSPVI SPIKSLPFSP SHFLKSPCLT TFEDMDLRAS TPVTKVYNRV 420
  421 GMEIKKEMET SSIETPHKSQ LGPRTPTPFK KALAAIGKKR DGRRYEPSSP SSLVEDLAEI 480
  481 IHEEHLSNSL TANNSKMMGA ADQNSTLSTE YNAQSPPHMK RARKSLLSTW SSNHPYNAGS 540
  541 AKRIQPFETE TPSKFLTSPG DILKDTLCSE QDLPFDEGRK ENRPFHNRRI NKYRGGLTYD 600
  601 HVIDPKWARV ACGKSRDQMF MEEQAYACLK NLSCISRSLN FEKQKCLVNS FDRFGSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 40.69897 v-Myb
    2 View Details [85..238] PSI-BLAST 46.39794 c-Myb, DNA-binding domain
    3 View Details [239..367] deduced N/A No confident structure predictions are available.
    4 View Details [368..580] Pfam 5.49485 No description for PF09316.1 was found. No confident structure predictions are available.
    5 View Details [581..657] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.14048290764066 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.666799964992178 bayes_pls_golite062009
  • actin binding
    		•  0.618026108235131 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.187022204923867 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle