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Protein Overview: CG12398-PA

General Information:
Name(s) found: CG12398-PA / FBpp0073793 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG12398 (CG12398, FBgn0030596). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14805876..14807830. It has the cytological map location 13A1. Based on sequence similarity, it is predicted to have molecular function</span>: glucose dehydrogenase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: alcohol metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 633 amino acids

    Gene Ontology:
    Cellular Component: chorion [IDA]
    Biological Process: alcohol metabolic process [IEA]
    Molecular Function: FAD binding [IEA]
    glucose dehydrogenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAINTFVAM WRFLLTLGPS AMIILLLNKG ILEQRPDIVD EQHRVRSIHI EDLRESYDFI  60
   61 VIGGGSAGCV LAARLSENPE WSVLLLEAGG DEPLLIDLPQ LYPVFQRSPW DWKYLTEPSD 120
  121 RYCLAMEDQR CFWPRAKVLG GCSSINAMMY IRGNRRDYDQ WAALGNPGWN YDNILHYFRK 180
  181 LEDMRVPGFE HSPYHGHGGP ISVERYRFPS PLLDIFMRAA QQLGMVHPDG DFNGRSQTGF 240
  241 APPHGSLRDG LRCSANKGYI RRSWQRPNLD IVLKAFVERI VIDPQSHRAI GVIFEYGLLK 300
  301 HTVRAKREVI LSAGSLASPQ LLMVSGVGPR DQLEPQGIPV VQHLPGVGGN LQDHISTSGA 360
  361 IYTFDSGQNR HLSFIVPEMM NEQAVEDFVQ GSDSFFYAMP VSEVMGFFST RYQDPRLDWP 420
  421 DVQIFMGSYG YGADGGMIGR RGAAITLDNY AEAFEPVLYQ DSFVIAPLLM RPRSRGYLQL 480
  481 RSADPKVHPL IHANYYDDPH DMAVMVEGLK LAHRLTQTPV MQSLNATMNI YEWRNCPEVE 540
  541 YLSDAFWECL ARFYSQTIYH PVGTCKMAPA SDPAGVVDPR LRVRGMRGLR VIDASIMPTI 600
  601 PTGNTNAPTL MLAERGADII KEDWRHYRDG GWG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..633] PSI-BLAST 89.154902 Glucose oxidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • choline dehydrogenase activity
    		•  4.66965094791663 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  4.10319574017291 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.3417445147889 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  1.47575323060551 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  1.34149762265767 bayes_pls_golite062009
  • glucose dehydrogenase activity
    		•  1.30840878956762 bayes_pls_golite062009
  • transporter activity
    		•  1.29839290134235 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.07862908893913 bayes_pls_golite062009
  • catalytic activity
    		•  1.03127962968326 bayes_pls_golite062009
  • monooxygenase activity
    		•  0.72374980280274 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.704326257168965 bayes_pls_golite062009
  • binding
    		•  0.694618787489897 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.556967966402473 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  0.442625746935807 bayes_pls_golite062009
  • protein binding
    		•  0.370064403093958 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.31459693204333 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  0.242456601435627 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  0.170082356807927 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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