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Protein Overview: CG11674-PA

General Information:
Name(s) found: CG11674-PA / FBpp0073743 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11674 (CG11674, FBgn0030551). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:14118676..14119917. It has the cytological map location 12E5. Based on sequence similarity, it is predicted to have molecular function</span>: ATP-dependent RNA helicase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nuclear mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: spliceosomal complex [ISS]
    Biological Process: nuclear mRNA splicing, via spliceosome [ISS]
    Molecular Function: ATP-dependent RNA helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAMHRWILL LLAGFLATGR AEDLLELSCS SDAQCAQFER GRCVDMACIC TARGSGERVP  60
   61 CTPLEERLKL TNIIGGACPC PMPNAICHTR WQQCHCSEGH VSSDDRRRCL PAVVPVGGSC 120
  121 EFQQQCQRAD RFSSCIGNQC LCLNQFEFHE GRCLSVLQSS CLEDKDCGSC GASICLTKTK 180
  181 RCGCSKNFVH NHNMTKCIKG SAYGDTCEHS SPCKLNLGAD GRCLDHLCVC RSTHYPKRVA 240
  241 NEVAKDENDD LDAVNNLERI TCAPIVPFGA LCRNDSECRM QPMDQENATA SIGHPMVCNW 300
  301 GECSCSKTHR LEDNKCVFVE NSATNYQLRG FVAFLCIQFT MILY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..344] PSI-BLAST 6.39794 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.3864568159494 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.99982263597244 bayes_pls_golite062009
  • structural molecule activity
    		•  1.5042961081297 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.44951301254545 bayes_pls_golite062009
  • transcription factor binding
    		•  1.34936656692122 bayes_pls_golite062009
  • protein binding
    		•  1.27903260513233 bayes_pls_golite062009
  • receptor binding
    		•  0.255196332544063 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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