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Protein Overview: gi|22832176, gi|...

General Information:
Name(s) found: gi|24641718 [NCBI NR]
gi|22832176 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|24641718|ref|NP_572868.2| HDAC4, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|22832176|gb|AAF48245.2| HDAC4, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1248 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    histone deacetylase complex [IEA]
    Biological Process: chromatin modification [IEA]
    regulation of transcription [IDA]
    Molecular Function: histone deacetylase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPDDRIPI HDLPSEAGSD ERLLHITPAT LTLDFKPHPA VDIDQQIMEL KKSQELQKQR  60
   61 LINSFQEQSK QMELEHKLQL EHKYQFAVNS HGAFQELRNE SMVTAAAAAV AQEQHRQQLH 120
  121 QQQQQHQQQQ QQQQHQQQQQ QQQARGRDGM KLKQNCSANA SPEVKQILNC FILSRKSQAA 180
  181 ASNGTTTTSP YRNRGVVKSS SGESLPAGTV TSAHPYKIPQ PPPSLLKYES DFPLRKTASE 240
  241 PNLLKIRLKQ SVIERKARIG GPAGARRHER LLQAAQRRQQ KNSVLTNCNS TPDSGPNSPP 300
  301 SAAALAVGVV GSRGSPTSAP IQEENEEGSQ YQPGQRSSIN DLPLFSSPSL PNISLGRPHL 360
  361 PNSAQAHAQV NAQVAAQAQA QAQAQAQAHA MFAALAAAQG GCGQPGYYNP LGMAFVGRQP 420
  421 APLAMIPATG IAPQQPSPVV RSASATSTSS SQASLVGDVA PPQAHAASTI LPSSSSYMQQ 480
  481 LGSVAGSGVN LHAAAVAAAA AAAAAAGSLP PTNSHGHGHG SHAHPHPHAH GHGHGHGHGI 540
  541 YAGHQHNVPI TDAQVAQVHL HKQGHRPLGR TQSAPLPLGH PMLTGAVQLN VVQTHYENSE 600
  601 AERQAYEHQV VNQKVRQTVL TRSGAAAAAA AAAGVSVVRE AQLKEEDDDS AAEVMDLTDK 660
  661 KKPPKTVLTS TIATSTSQNL PEALAAAAAA AAYRAPHNAS SNSASATKSG IKLRDQEYLQ 720
  721 QQREQLLLLQ QEEELAKSLM RPLSRTLSSP LVPLGPHGLS QIPDTGQQPA PIATSSSADH 780
  781 IPPVNLSLPH RQHRQLMSTL YASQLRNHQP SASGSPPHKV TTGLAYDPLM LKHSCICGDN 840
  841 AQHPEHSGRL QSVWARLNET DLVKRCDRLR ARKATQEELQ TVHTEAHAML FGSNQCQLSR 900
  901 PKLENTLSAS FVRLSCGGLG VDLDTTWNEH HTATAARMAA GCVIDLALKT AKGDLRNGFA 960
  961 VVRPPGHHAE ANLAMGFCFF NSIAIAAKLL RQRMPEVRRI LIVDWDVHHG NGTQQAFYQS1020
 1021 PDILYLSIHR HDDGNFFPGT GGPTECGSGA GLGFNVNISW SGALNPPLGD AEYIAAFRTV1080
 1081 VMPIARSFNP DIVLVSSGFD AATGHPAPLG GYHVSPACFG FMTRELLQLA NGKVVLALEG1140
 1141 GYDLAAICDS AQECVRALLG DPAAPIAKAE LERPPCQNAI NTLQKTIAIQ QTHWPCVRML1200
 1201 EHTVGLSALE TLKVEHDESE TINAMAGLSM QTLSRDDSEE PMDQDETK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] PSI-BLAST 12.522879 No description for 2i1jA was found.
    2 View Details [179..382] deduced N/A No confident structure predictions are available.
    3 View Details [383..534] MSA 2.359996 View MSA. No confident structure predictions are available.
    4 View Details [535..743] deduced N/A No confident structure predictions are available.
    5 View Details [744..1248] PSI-BLAST 125.0 No description for 2pqoA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle