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View Structure Prediction Details

Protein: gi|22832176, gi|...
Organism: Drosophila melanogaster
Length: 1248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|22832176, gi|....

Description E-value Query
Range
Subject
Range
gi|23194387 - gi|23194387|gb|AAN15143.1| histone deacetylase dHDAC4 isoform b [Drosophila melanogaster]
613.0 [0..1] [1248..1]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPDDRIPI HDLPSEAGSD ERLLHITPAT LTLDFKPHPA VDIDQQIMEL KKSQELQKQR  60
   61 LINSFQEQSK QMELEHKLQL EHKYQFAVNS HGAFQELRNE SMVTAAAAAV AQEQHRQQLH 120
  121 QQQQQHQQQQ QQQQHQQQQQ QQQARGRDGM KLKQNCSANA SPEVKQILNC FILSRKSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #2
Region A:
Residues: [179-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAASNGTTTT SPYRNRGVVK SSSGESLPAG TVTSAHPYKI PQPPPSLLKY ESDFPLRKTA  60
   61 SEPNLLKIRL KQSVIERKAR IGGPAGARRH ERLLQAAQRR QQKNSVLTNC NSTPDSGPNS 120
  121 PPSAAALAVG VVGSRGSPTS APIQEENEEG SQYQPGQRSS INDLPLFSSP SLPNISLGRP 180
  181 HLPNSAQAHA QVNAQVAAQA QAQA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [383-534]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAQAQAHAMF AALAAAQGGC GQPGYYNPLG MAFVGRQPAP LAMIPATGIA PQQPSPVVRS  60
   61 ASATSTSSSQ ASLVGDVAPP QAHAASTILP SSSSYMQQLG SVAGSGVNLH AAAVAAAAAA 120
  121 AAAAGSLPPT NSHGHGHGSH AHPHPHAHGH GH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [535-743]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHGHGIYAGH QHNVPITDAQ VAQVHLHKQG HRPLGRTQSA PLPLGHPMLT GAVQLNVVQT  60
   61 HYENSEAERQ AYEHQVVNQK VRQTVLTRSG AAAAAAAAAG VSVVREAQLK EEDDDSAAEV 120
  121 MDLTDKKKPP KTVLTSTIAT STSQNLPEAL AAAAAAAAYR APHNASSNSA SATKSGIKLR 180
  181 DQEYLQQQRE QLLLLQQEEE LAKSLMRPL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [744-1248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRTLSSPLVP LGPHGLSQIP DTGQQPAPIA TSSSADHIPP VNLSLPHRQH RQLMSTLYAS  60
   61 QLRNHQPSAS GSPPHKVTTG LAYDPLMLKH SCICGDNAQH PEHSGRLQSV WARLNETDLV 120
  121 KRCDRLRARK ATQEELQTVH TEAHAMLFGS NQCQLSRPKL ENTLSASFVR LSCGGLGVDL 180
  181 DTTWNEHHTA TAARMAAGCV IDLALKTAKG DLRNGFAVVR PPGHHAEANL AMGFCFFNSI 240
  241 AIAAKLLRQR MPEVRRILIV DWDVHHGNGT QQAFYQSPDI LYLSIHRHDD GNFFPGTGGP 300
  301 TECGSGAGLG FNVNISWSGA LNPPLGDAEY IAAFRTVVMP IARSFNPDIV LVSSGFDAAT 360
  361 GHPAPLGGYH VSPACFGFMT RELLQLANGK VVLALEGGYD LAAICDSAQE CVRALLGDPA 420
  421 APIAKAELER PPCQNAINTL QKTIAIQQTH WPCVRMLEHT VGLSALETLK VEHDESETIN 480
  481 AMAGLSMQTL SRDDSEEPMD QDETK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.0
Match: 2pqoA
Description: No description for 2pqoA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle