Protein Overview: Hsc70-3-PA, Hsc7...

General Information:
Name(s) found:	FBpp0311376 [FlyBase] Hsc70-3-PC / FBpp0073448 [FlyBase] Hsc70-3-PD / FBpp0073447 [FlyBase] Hsc70-3-PA / FBpp0073446 [FlyBase] Hsc70-3-PB / FBpp0073445 [FlyBase]
Description(s) found: Found 71 descriptions. SHOW ALL	type=protein; loc=X:complement(11696646..11698491,11698930..11699054); ID=FBpp0311376; name=Hsc70-3-PE; parent=FBgn0001218,FBtr0345166; dbxref=FlyBase:FBpp0311376,FlyBase_Annotation_IDs:CG4147-PE; MD5=90cfc2d2c129e8a211bff4d9b740fb53; length=656; release=r5.56; species=Dmel; [FlyBase] The gene Heat shock protein cognate 3 is referred to in FlyBase by the symbol Dmel\Hsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11695729..11701212. It has the cytological map location 10E3-10E4. It is reported to have molecular function</span>: ATPase activity. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 40 alleles are reported. The phenotypes of these alleles are annotated with: pupa; eye; ommatidium; third instar larva. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Heat shock protein cognate 3 is referred to in FlyBase by the symbol Dmel\Hsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11695729..11701212. It has the cytological map location 10E3-10E4. It is reported to have molecular function</span>: ATPase activity. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 40 alleles are reported. The phenotypes of these alleles are annotated with: pupa; eye; ommatidium; third instar larva. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Heat shock protein cognate 3 is referred to in FlyBase by the symbol Dmel\Hsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11695729..11701212. It has the cytological map location 10E3-10E4. It is reported to have molecular function</span>: ATPase activity. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 40 alleles are reported. The phenotypes of these alleles are annotated with: pupa; eye; ommatidium; third instar larva. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Heat shock protein cognate 3 is referred to in FlyBase by the symbol Dmel\Hsc70-3 (CG4147, FBgn0001218). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11695729..11701212. It has the cytological map location 10E3-10E4. It is reported to have molecular function</span>: ATPase activity. There is experimental evidence that it is involved in the biological process</span>: RNA interference. 40 alleles are reported. The phenotypes of these alleles are annotated with: pupa; eye; ommatidium; third instar larva. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	656 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] endoplasmic reticulum [IDA][NAS]
Biological Process:	response to heat [ISS][NAS] sleep [TAS] RNA interference [IMP]
Molecular Function:	ATPase activity [NAS] ATP binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLCILLAVV AFVGLSLGEE KKEKDKELGT VIGIDLGTTY SCVGVYKNGR VEIIANDQGN  60
   61 RITPSYVAFT ADGERLIGDA AKNQLTTNPE NTVFDAKRLI GREWSDTNVQ HDIKFFPFKV 120
  121 VEKNSKPHIS VDTSQGAKVF APEEISAMVL GKMKETAEAY LGKKVTHAVV TVPAYFNDAQ 180
  181 RQATKDAGVI AGLQVMRIIN EPTAAAIAYG LDKKEGEKNV LVFDLGGGTF DVSLLTIDNG 240
  241 VFEVVATNGD THLGGEDFDQ RVMDHFIKLY KKKKGKDIRK DNRAVQKLRR EVEKAKRALS 300
  301 GSHQVRIEIE SFFEGDDFSE TLTRAKFEEL NLDLFRSTLK PVQKVLEDAD MNKKDVHEIV 360
  361 LVGGSTRIPK VQQLVKDFFG GKEPSRGINP DEAVAYGAAV QAGVLSGEQD TDAIVLLDVN 420
  421 PLTMGIETVG GVMTKLIPRN TVIPTKKSQV FSTASDNQHT VTIQVYEGER PMTKDNHLLG 480
  481 KFDLTGIPPA PRGIPQIEVS FEIDANGILQ VSAEDKGTGN KEKIVITNDQ NRLTPEDIDR 540
  541 MIRDAEKFAD EDKKLKERVE SRNELESYAY SLKNQIGDKD KLGAKLSDDE KNKLESAIDE 600
  601 SIKWLEQNPD ADPEEYKKQK KDLEAIVQPV IAKLYQGAGG APPPEGGDDA DLKDEL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..584]	PSI-BLAST	1000.0	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
2	View Details	[585..656]	PSI-BLAST	55.69897	DnaK

Protein Overview: Hsc70-3-PA, Hsc7...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: