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Protein Overview: Ubi-p5E-PA, FBpp...

General Information:
Name(s) found: FBpp0311816 [FlyBase]
Ubi-p5E-PA / FBpp0070894 [FlyBase]
Description(s) found:
Found 25 descriptions.
SHOW ALL
  • type=protein; loc=X:complement(6171177..6172781); ID=FBpp0311816; name=Ubi-p5E-PB; parent=FBgn0086558,FBtr0345892; dbxref=FlyBase:FBpp0311816,FlyBase_Annotation_IDs:CG32744-PB; MD5=e647e40d6d877d42214ce3f015f4d7a0; length=534; release=r5.56; species=Dmel; [FlyBase]
  • The gene Ubiquitin-5E is referred to in FlyBase by the symbol Dmel\Ubi-p5E (CG32744, FBgn0086558). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6171010..6173304. It has the cytological map location 5E4. Based on sequence similarity, it is predicted to have molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: ubiquitin-dependent protein catabolic process; protein modification process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 534 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome band [IDA]
    Biological Process: protein modification process [ISS]
    ubiquitin-dependent protein catabolic process [ISS]
    Molecular Function: protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN  60
   61 IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVEPSDTIE NVKAKIQDKE GIPPDQQRLI 120
  121 FAGKQLEDGR TLSDYNIQKE STLHLVLRLR GGMQIFVKTL TGKTITLEVE PSDTIENVKA 180
  181 KIQDKEGIPP DQQRLIFAGK QLEDGRTLSD YNIQKESTLH LVLRLRGGMQ IFVKTLTGKT 240
  241 ITLEVEPSDT IENVKAKIQD KEGIPPDQQR LIFAGKQLED GRTLSDYNIQ KESTLHLVLR 300
  301 LRGGMQIFVK TLTGKTITLE VEPSDTIENV KAKIQDKEGI PPDQQRLIFA GKQLEDGRTL 360
  361 SDYNIQKEST LHLVLRLRGG MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ 420
  421 QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVEPSDTIE 480
  481 NVKAKIQDKE GIPPDQQRLI FAGKQLEDGR TLSDYNIQKE STLHLVLRLR GGAI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] PSI-BLAST 30.09691 Solution Structure of S5a UIM-1/Ubiquitin Complex
    2 View Details [85..227] FFAS03 4.84 Crystal Structure of ISG15, the Interferon-Induced Ubiquitin Cross Reactive Protein
    3 View Details [228..339] PSI-BLAST 4.30103 Elongin B
    4 View Details [340..455] PSI-BLAST 13.0 Solution structure of Ubiquitin-like domain in SF3a120
    5 View Details [456..534] PSI-BLAST 28.0 Crystal structure of a multiple hydrophobic core mutant of ubiquitin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  7.96815122865454 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  7.5865326390755 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.96506647680367 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.87890364671564 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.80275625219016 bayes_pls_golite062009
  • structural molecule activity
    		•  5.37716040292459 bayes_pls_golite062009
  • ligase activity
    		•  2.98370000660434 bayes_pls_golite062009
  • protein binding
    		•  2.9188688008729 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21955949922709 bayes_pls_golite062009
  • tubulin binding
    		•  2.21127283188349 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20811136250556 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.9984951714209 bayes_pls_golite062009
  • microtubule binding
    		•  1.92602521631666 bayes_pls_golite062009
  • DNA binding
    		•  1.86539227646379 bayes_pls_golite062009
  • receptor binding
    		•  1.09091623056284 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.06193722939839 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.62324312069889 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • RNA binding
    		•  0.359926300264681 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.27796076785312 bayes_pls_golite062009
  • enzyme binding
    		•  0.240262781026149 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.189489510504993 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0788219117963673 bayes_pls_golite062009
    2
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  7.77976521481104 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  7.45825282569124 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.82424077726436 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.78164148882937 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.77326793355348 bayes_pls_golite062009
  • structural molecule activity
    		•  5.36311620867914 bayes_pls_golite062009
  • ligase activity
    		•  2.93949076291021 bayes_pls_golite062009
  • protein binding
    		•  2.78014377544701 bayes_pls_golite062009
  • binding
    		•  2.70872150536621 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.23822335492051 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.11984570584255 bayes_pls_golite062009
  • tubulin binding
    		•  2.03607606145909 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.02209816078273 bayes_pls_golite062009
  • DNA binding
    		•  1.8833926783115 bayes_pls_golite062009
  • microtubule binding
    		•  1.75926256048235 bayes_pls_golite062009
  • protein tag
    		•  1.64936739586738 bayes_pls_golite062009
  • receptor binding
    		•  1.07983643886476 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.04462787665591 bayes_pls_golite062009
  • hydrolase activity
    		•  0.633589926944629 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.624731467637361 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.549761413791307 bayes_pls_golite062009
  • kinase activity
    		•  0.520011006272513 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.469920108401949 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.426082194130922 bayes_pls_golite062009
  • RNA binding
    		•  0.3655923364304 bayes_pls_golite062009
  • protein kinase activity
    		•  0.336252604607827 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.270602640718893 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.181054590240182 bayes_pls_golite062009
  • enzyme binding
    		•  0.147520546067615 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0623044995795676 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  7.96815122865454 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  7.5865326390755 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.96506647680367 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.87890364671564 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.80275625219016 bayes_pls_golite062009
  • structural molecule activity
    		•  5.37716040292459 bayes_pls_golite062009
  • ligase activity
    		•  2.98370000660434 bayes_pls_golite062009
  • protein binding
    		•  2.9188688008729 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21955949922709 bayes_pls_golite062009
  • tubulin binding
    		•  2.21127283188349 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20811136250556 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.9984951714209 bayes_pls_golite062009
  • microtubule binding
    		•  1.92602521631666 bayes_pls_golite062009
  • DNA binding
    		•  1.86539227646379 bayes_pls_golite062009
  • receptor binding
    		•  1.09091623056284 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.06193722939839 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.62324312069889 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • RNA binding
    		•  0.359926300264681 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.27796076785312 bayes_pls_golite062009
  • enzyme binding
    		•  0.240262781026149 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.189489510504993 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0788219117963673 bayes_pls_golite062009
    5
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  7.96815122865454 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  7.5865326390755 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.96506647680367 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.87890364671564 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.80275625219016 bayes_pls_golite062009
  • structural molecule activity
    		•  5.37716040292459 bayes_pls_golite062009
  • ligase activity
    		•  2.98370000660434 bayes_pls_golite062009
  • protein binding
    		•  2.9188688008729 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.21955949922709 bayes_pls_golite062009
  • tubulin binding
    		•  2.21127283188349 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.20811136250556 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.9984951714209 bayes_pls_golite062009
  • microtubule binding
    		•  1.92602521631666 bayes_pls_golite062009
  • DNA binding
    		•  1.86539227646379 bayes_pls_golite062009
  • receptor binding
    		•  1.09091623056284 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.06193722939839 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.62324312069889 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • RNA binding
    		•  0.359926300264681 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  0.27796076785312 bayes_pls_golite062009
  • enzyme binding
    		•  0.240262781026149 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  0.189489510504993 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0788219117963673 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle