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Protein Overview: FBpp0311766, dhd-PA

General Information:
Name(s) found: FBpp0311766 [FlyBase]
dhd-PA / FBpp0070717 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • type=protein; loc=X:5206493..5206816; ID=FBpp0311766; name=dhd-PB; parent=FBgn0011761,FBtr0345745; dbxref=FlyBase:FBpp0311766,FlyBase_Annotation_IDs:CG4193-PB; MD5=a36ade5b4ba7df96ebe2c72e2259b7d9; length=107; release=r5.56; species=Dmel; [FlyBase]
  • The gene deadhead is referred to in FlyBase by the symbol Dmel\dhd (CG4193, FBgn0011761). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5206406..5207155. It has the cytological map location 4F4. There is experimental evidence that it has the molecular function</span>: disulfide oxidoreductase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 107 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS]
    Biological Process: embryonic development [NAS]
    female meiosis [NAS]
    cell redox homeostasis [IEA]
    response to DNA damage stimulus [IMP]
    Molecular Function: disulfide oxidoreductase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASVRTMNDY HKRIEAADDK LIVLDFYATW CGPCKEMEST VKSLARKYSS KAVVLKIDVD  60
   61 KFEELTERYK VRSMPTFVFL RQNRRLASFA GADEHKLTNM MAKLVKA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 29.522879 Thioredoxin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antioxidant activity
    		•  3.8464796631544 bayes_pls_golite062009
  • peroxidase activity
    		•  3.43831566988273 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  3.43831566988273 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.56524997297011 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.23310780102446 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.32811008894503 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.96297634785608 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • hydrolase activity
    		•  0.620302638089385 bayes_pls_golite062009
  • glutathione binding
    		•  0.2456976890622 bayes_pls_golite062009
  • protein binding
    		•  0.134341907247724 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  0.0719543694089202 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle