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Protein Overview: fs(1)Yb-PA

General Information:
Name(s) found: fs(1)Yb-PA / FBpp0070462 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene female sterile (1) Yb is referred to in FlyBase by the symbol Dmel\fs(1)Yb (CG2706, FBgn0000928). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2614501..2618192. It has the cytological map location 3B3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ATP binding; ATP-dependent helicase activity; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; oogenesis; germ cell development; germ-line stem cell division. 28 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: anatomical structure; organ system; female germline cyst; egg; organism; germarium; cytoplasmic part; germline cell; chorion; intracellular non-membrane-bounded organelle; spectrosome. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1042 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    Yb body [IDA]
    Biological Process: germ cell development [IMP]
    ovarian follicle cell stalk formation [TAS]
    oogenesis [IMP]
    somatic stem cell division [TAS]
    germ-line stem cell maintenance [IMP]
    germ-line stem cell division [IMP][TAS]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    ATP-dependent helicase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPIGDLQVP SFKVVSGGTT FTYASPKSGA ASLDFLAHTL RKREANTEKT ILICQQNFEA  60
   61 ERLKFELAER DVNTILLPPH GAMVGQVLLL WSKGYINQAL ILCDGMLEHL GVVEANLVIH 120
  121 TTLPELNKFE ERLKWLSISA RNAEMLVITP CDEENEKEGK GETEPEIVQQ RMPLKVDALN 180
  181 SMQLYEIKEN TPPTSSEDYK AEADVLLSAA TPATIPNDNK EQEINLSVED ATVKLLASFE 240
  241 LGSTDSAAVD ESSPAAAKFN APVYSPFVTE NPTKSLDAEF QELVKSFKVQ NVFKNMNLPP 300
  301 PPSVSIEEPV SSASASDYRH QIDTTSLDSI RTVKDSPASL AVVPFSAGGI TYNNYGVLGW 360
  361 SRHAVVPCYG LTEAPDISTI IRRAMQQMGV ARSRARAVQR FAWPHVSLGK SVLVVGNLQI 420
  421 GKTWSYLPTV CQRSHEDLQR RPDVGRGPTC IFVCPNQGQG KQIERWMSTL LCLLGSASGF 480
  481 EDVVTHWDKT QLVDIVRRLK KPVGILLTSV DLLLQLLNHN PVGSIFDAQA VKCIALDNLN 540
  541 DMVRVLPNDT MKLLQRLPEM FQLTQNKCQL LVSGRIWHTD LMVQHILPLM PDVLVLFDDA 600
  601 LEASVYGGVQ LDVRVVADEP EKIEHLKALI AERRNFANEP AVMVCSNSTE VLLLRRSLQA 660
  661 IGVNAHICVS EACYSNVAEW LRQSPSGLLL VTDDVVPRLK CGKIPLLIHY SFASMWARFK 720
  721 NRFSLFYANL KSPTTRPVGQ SVVFAKPTDL ENIWKLCDFY MKHKLPRPGH LLGILSQRRL 780
  781 EEQPTSRSLC HQMAAFGDCL RHKCMYRHVM WRDEVLPPDH YPKNGLIRFL VLVCYSPAAL 840
  841 AVRLSDQFPT AIRFLNFPMS DLGERVQRHY ELEANRHMHP NPVPGEMAVV KNINRYERVH 900
  901 IVSVESNVMV LVQLLDTSTE CFSYKTSQLY SCDKIFKDSP REAMDLRILG LQPESLDRIW 960
  961 PDDARNLVRK DFFRRTHNKR NRQFHAVVQS AIHRTIFVRN IYDDEGNDLL SFVINRFRSH1020
 1021 QDECCQLKLD AMVMSSKDCP YM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..121] deduced N/A No confident structure predictions are available.
    2 View Details [122..361] MSA 2.490996 View MSA. No confident structure predictions are available.
    3 View Details [362..786] PSI-BLAST 87.221849 No description for 2i4iA was found.
    4 View Details [787..1042] PSI-BLAST 8.522879 No description for 2hqeA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.39943347346873 bayes_pls_golite062009
  • protein binding
    		•  1.76914488602752 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.87394330322458 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.51916143359824 bayes_pls_golite062009
  • transcription factor binding
    		•  0.41343456527013 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle