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Protein Overview: deltaCOP-PA

General Information:
Name(s) found: deltaCOP-PA / FBpp0070355 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Ã?&#142;Ã?´-coatomer protein is referred to in FlyBase by the symbol Dmel\Ã?&#142;Ã?´COP (CG14813, FBgn0028969). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1753174..1755825. It has the cytological map location 2B12-2B13. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 532 amino acids

    Gene Ontology:
    Cellular Component: clathrin adaptor complex [IEA]
    COPI vesicle coat [ISS][NAS]
    Biological Process: phagocytosis, engulfment [IMP]
    retrograde vesicle-mediated transport, Golgi to ER [ISS]
    intracellular protein transport [IEA]
    Molecular Function: protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLIAAAVCT KNGKVILSRQ FVEMTKARIE GLLAAFPKLM TAGKQHTYVE TDSVRYVYQP  60
   61 MEKLYMLLIT TKASNILEDL ETLRLFSKVI PEYSHSLDEK EIVENAFNLI FAFDEIVALG 120
  121 YRESVNLAQI KTFVEMDSHE EKVYQAVRQT QERDARQKMR EKAKELQRQR MEASKRGGPS 180
  181 LGGIGSRSGG FSADGIGSSG VSSSSGASSA NTGITSIDVD TKSKAAASKP ASRNALKLGG 240
  241 KSKDVDSFVD QLKNEGEKIA NLAPAAPAGG SSAAASASAA AKAAIASDIH KESVHLKIED 300
  301 KLVVRLGRDG GVQQFENSGL LTLRITDEAY GRILLKLSPN HTQGLQLQTH PNVDKELFKS 360
  361 RTTIGLKNLG KPFPLNTDVG VLKWRFVSQD ESAVPLTINC WPSDNGEGGC DVNIEYELEA 420
  421 QQLELQDVAI VIPLPMNVQP SVAEYDGTYN YDSRKHVLQW HIPIIDAANK SGSMEFSCSA 480
  481 SIPGDFFPLQ VSFVSKTPYA GVVAQDVVQV DSEAAVKYSS ESILFVEKYE IV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 37.09691 AP1 clathrin adaptor core
    2 View Details [135..532] PSI-BLAST 65.0 Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • clathrin binding
    		•  4.44604247436673 bayes_pls_golite062009
  • protein-cysteine S-palmitoleyltransferase activity
    		•  4.29882837485966 bayes_pls_golite062009
  • protein-cysteine S-acyltransferase activity
    		•  4.29882837485966 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  2.42277624456482 bayes_pls_golite062009
  • SNAP receptor activity
    		•  2.23518960752054 bayes_pls_golite062009
  • transporter activity
    		•  1.6020979054057 bayes_pls_golite062009
  • protein transporter activity
    		•  1.50978938003272 bayes_pls_golite062009
  • binding
    		•  1.47935906574431 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.21465932013369 bayes_pls_golite062009
  • protein binding
    		•  1.10098179099023 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.890040378421594 bayes_pls_golite062009
  • palmitoyltransferase activity
    		•  0.76687594030379 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.131410992694836 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0936690070284361 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0846345824909659 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0820309452260982 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle