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View Structure Prediction Details

Protein: deltaCOP-PA
Organism: Drosophila melanogaster
Length: 532 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for deltaCOP-PA.

Description E-value Query
Range
Subject
Range
gi|73954687 - gi|73954687|ref|XP_860561.1| PREDICTED: similar to archain isoform 2 [Canis familiaris]
403.0 [0..1] [532..1]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLIAAAVCT KNGKVILSRQ FVEMTKARIE GLLAAFPKLM TAGKQHTYVE TDSVRYVYQP  60
   61 MEKLYMLLIT TKASNILEDL ETLRLFSKVI PEYSHSLDEK EIVENAFNLI FAFDEIVALG 120
  121 YRESVNLAQI KTFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.09691
Match: 1w63Q
Description: AP1 clathrin adaptor core
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [135-532]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMDSHEEKVY QAVRQTQERD ARQKMREKAK ELQRQRMEAS KRGGPSLGGI GSRSGGFSAD  60
   61 GIGSSGVSSS SGASSANTGI TSIDVDTKSK AAASKPASRN ALKLGGKSKD VDSFVDQLKN 120
  121 EGEKIANLAP AAPAGGSSAA ASASAAAKAA IASDIHKESV HLKIEDKLVV RLGRDGGVQQ 180
  181 FENSGLLTLR ITDEAYGRIL LKLSPNHTQG LQLQTHPNVD KELFKSRTTI GLKNLGKPFP 240
  241 LNTDVGVLKW RFVSQDESAV PLTINCWPSD NGEGGCDVNI EYELEAQQLE LQDVAIVIPL 300
  301 PMNVQPSVAE YDGTYNYDSR KHVLQWHIPI IDAANKSGSM EFSCSASIPG DFFPLQVSFV 360
  361 SKTPYAGVVA QDVVQVDSEA AVKYSSESIL FVEKYEIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.0
Match: 1gw5M
Description: Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; Mu2 adaptin (clathrin coat assembly protein AP50)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
clathrin binding 4.44604247436673 bayes_pls_golite062009
protein-cysteine S-palmitoleyltransferase activity 4.29882837485966 bayes_pls_golite062009
protein-cysteine S-acyltransferase activity 4.29882837485966 bayes_pls_golite062009
S-acyltransferase activity 2.42277624456482 bayes_pls_golite062009
SNAP receptor activity 2.23518960752054 bayes_pls_golite062009
transporter activity 1.6020979054057 bayes_pls_golite062009
protein transporter activity 1.50978938003272 bayes_pls_golite062009
binding 1.47935906574431 bayes_pls_golite062009
signal recognition particle binding 1.21465932013369 bayes_pls_golite062009
protein binding 1.10098179099023 bayes_pls_golite062009
substrate-specific transporter activity 0.890040378421594 bayes_pls_golite062009
palmitoyltransferase activity 0.76687594030379 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.131410992694836 bayes_pls_golite062009
pyrophosphatase activity 0.0936690070284361 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0846345824909659 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0820309452260982 bayes_pls_golite062009

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