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Protein Overview: CG42666-PB

General Information:
Name(s) found: CG42666-PB / FBpp0291794 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG42666 (CG42666, FBgn0261548).The gene has a gene model, but the supporting evidence is inconclusive. It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1719693..1746966. It has the cytological map location 2B10-2B12. Based on sequence similarity, it is predicted to have molecular function</span>: exonuclease activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 787 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: NONE FOUND
    Molecular Function: nucleic acid binding [IEA]
    exonuclease activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQITNYFEH MDYVSFSVVA LPCVVIAVYG FLQVASGLAK CKNDKMQSCN KNSSSRITTT  60
   61 NNNVTTTSNI SGNSSNKRCP QKYTGNTLAV NSNMLAYQQQ ATAGGKNSTR KSRHNNNKQN 120
  121 HQQQQQQQQQ QFDHIHKRNG TAGGTGSECS PAAPTSNWLQ RGYGRQFVHS SCIEDKLLGH 180
  181 HNPGHRNSTS SDATSEDIDS SSELPNKSKG NSCAGSIHAS GGSKSRSKRH QKQSGQQTRN 240
  241 PDHNGQRTGA ATPCTGQKAK QGNAKWRQQQ PNPSSNNQQQ QMQQQMQQQK RGRNKKPGKW 300
  301 SNNIIDNPNS NHGGSSQQKT CDSSSSSALS SPTSSATTSA TSSPTNSPTS YPRANGNRKR 360
  361 IEAALEWRRE QELGRQNANF LVPPLRQYEQ LEFDDKTVVQ QLRRHIIDNH LLRVYGFPVD 420
  421 SVVHEGAIEI FKCMPHMSFA AALAETAQAV TVINYHDGLT NRAEEEVANS TDSGNSSPQS 480
  481 LDSESGGEWS GSECESSNSS SSSAGEAALG LELKYCHFVP VERSLSKPCA RCKRHFLVDE 540
  541 LTGQYLTHEE CQYHSGKYQR YYDGVSHGRW TCCNEGEESS PGCCLGDRHV WSGSVVGVNG 600
  601 PYYDFVRTEH RGSGEDEPAV YALDCEMSYT GRGLDVTKVS LVALNGQLVY EHFVRPVCDI 660
  661 IDYNTQYSGI TETDLCSGAK SLAEVQRDLL QLITADTILI GHGLENDLRA LRLVHNTLID 720
  721 TSISFPHCNG FPYRRALRHL TKVHLKRDIQ AGDGTTGHSS FEDSRACMEL MLWRVNRELD 780
  781 PAWSWDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..393] FFAS03 1.07 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    2 View Details [394..508] deduced N/A No confident structure predictions are available.
    3 View Details [509..612] FFAS03 1.01 No description for 2jm1A was found.
    4 View Details [613..787] PSI-BLAST 48.0 human ISG20

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • ribonuclease activity
    		•  5.30591758406946 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.71639182685131 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  3.59362615133405 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  3.1992647486402 bayes_pls_golite062009
  • exonuclease activity
    		•  3.13676176369406 bayes_pls_golite062009
  • nuclease activity
    		•  3.11657409772275 bayes_pls_golite062009
  • ribonuclease H activity
    		•  2.91966688044755 bayes_pls_golite062009
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
    		•  2.75003136922541 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.57498413015114 bayes_pls_golite062009
  • hydrolase activity
    		•  2.41899414621161 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  2.04408785855894 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  1.44123900197846 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.23371034593624 bayes_pls_golite062009
  • protein binding
    		•  1.16870279238939 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.1219517187744 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.10433412699603 bayes_pls_golite062009
  • DNA binding
    		•  0.860359347662869 bayes_pls_golite062009
  • binding
    		•  0.762139256580538 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.717600245625866 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.708753843279937 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.598360955770972 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.568273228950698 bayes_pls_golite062009
    		• 0.49473250705373 bayes_pls_golite062009
  • transcription factor activity
    		•  0.332903382446869 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.278838342302102 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.261428436029202 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0701825322473915 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.00214157813118243 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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