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Protein Overview: Rad23-PA, FBpp03...

General Information:
Name(s) found: FBpp0305835 [FlyBase]
Rad23-PA / FBpp0088191 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=4:join(328850..328915,329057..329705,330165..330259,330320..330643,330705..330815); ID=FBpp0305835; name=Rad23-PC; parent=FBgn0026777,FBtr0333679; dbxref=REFSEQ:NP_001259052,GB_protein:AGB96542,FlyBase:FBpp0305835,FlyBase_Annotation_IDs:CG1836-PC; MD5=17973ecc45005451bc00280842c2ca46; length=414; release=r5.56; species=Dmel; [FlyBase]
  • The gene Rad23 is referred to in FlyBase by the symbol Dmel\Rad23 (CG1836, FBgn0026777). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:328723..330934. It has the cytological map location 102B3. Based on sequence similarity, it is predicted to have molecular function</span>: damaged DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: nucleotide-excision repair. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IEA]
    nucleotide-excision repair [ISS][NAS]
    Molecular Function: damaged DNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIITIKNLQQ QTFTIEFAPE KTVLELKKKI FEERGPEYVA EKQKLIYAGV ILTDDRTVGS  60
   61 YNVDEKKFIV VMLTRDSSSS NRNQLSVKES NKLTSTDDSK QSMPCEEANH TNSPSSTNTE 120
  121 DSVLSRETRP LSSDELIGEL AQASLQSRAE SNLLMGDEYN QTVLSMVEMG YPREQVERAM 180
  181 AASYNNPERA VEYLINGIPA EEGTFYNRLN ESTNPSLIPS GPQPASATSA ERSTESNSDP 240
  241 FEFLRSQPQF LQMRSLIYQN PHLLHAVLQQ IGQTNPALLQ LISENQDAFL NMLNQPIDRE 300
  301 SESGATVPPV SNARIPSTLD NVDLFSPDLE VATSAQRSAA GTSAAHQSGS AADNEDLEQP 360
  361 LGVSTIRLNR QDKDAIERLK ALGFPEALVL QAYFACEKNE EQAANFLLSS SFDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] PSI-BLAST 47.69897 Structure of the DNA repair protein hHR23a

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • damaged DNA binding
    		•  4.47463096529128 bayes_pls_golite062009
  • peptidase activity
    		•  4.11397638448668 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  3.93085931991298 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  3.71144418714309 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  3.30801071565148 bayes_pls_golite062009
  • binding
    		•  2.786655943372 bayes_pls_golite062009
  • hydrolase activity
    		•  2.77871378503369 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  2.72499875710239 bayes_pls_golite062009
  • protein tag
    		•  2.15059229834935 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  2.00465244189638 bayes_pls_golite062009
  • protein binding
    		•  1.86841453215444 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.42747465816672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32707653701567 bayes_pls_golite062009
  • DNA binding
    		•  1.22622447288034 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.80391127659342 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  0.59805675560068 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.570143717979967 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.536856055841234 bayes_pls_golite062009
  • kinase activity
    		•  0.506057697290914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.410719674374641 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  0.387487703339719 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.366426020658587 bayes_pls_golite062009
  • protein kinase activity
    		•  0.325253662829604 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.249928925871521 bayes_pls_golite062009
  • transferase activity
    		•  0.236208643697075 bayes_pls_golite062009
  • polyubiquitin binding
    		•  0.126322128629172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle