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Protein Overview: Jon99Ci-PA

General Information:
Name(s) found: Jon99Ci-PA / FBpp0084877 [FlyBase]
Description(s) found:
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  • gi|7301864|gb|AAF56973.1| jonah 99Ci [Drosophila melanogaster] [NCBI NR]
  • gi|17986193|ref|NP_524555.1| jonah 99Ci [Drosophila melanogaster] [NCBI NR]
  • gi|17944369|gb|AAL48076.1| RE70942p [Drosophila melanogaster] [NCBI NR]
  • gi|12644135|sp|P17207.2|SER3_DROME RecName: Full=Serine protease 3; AltName: Full=Protein Jonah 99Ci; Flags: Precursor [NCBI NR]
  • Serine protease 3 OS=Drosophila melanogaster GN=Jon99Ci PE=2 SV=2 [Swiss-Prot]
  • The gene Jonah 99Ci is referred to in FlyBase by the symbol Dmel\Jon99Ci (CG31039, FBgn0003358). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25750948..25751907. It has the cytological map location 99C7. Based on sequence similarity, it is predicted to have molecular function</span>: serine-type endopeptidase activity. It is reported to be involved in the biological process</span>: digestion; proteolysis. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG31039-PA translation from_gene[CG31039 Ser99Dc FBgn0003358] seq_release:3 mol_weight=29620 cds_boundaries:(3R:25,740,390..25,741,262[-]) aa_length:272 transcript_info:[CG31039-RA seq_release:3] gene_info:[gene symbol:Ser99Dc synonyms:[CG17951] FBgn0 [hmr_yeast5_DM3-1_pombe.fasta]
  • (P17207) Serine protease 3 precursor (EC 3.4.21.-) [DrosMelano7227.FASTAC.txt]
  • (AE003771) Ser99Dc gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG31039-PA [Drosophila melanogaster]gi|17944369|gb|AAL48076.1| RE70942p [Drosophila melanogaster]gi|17986193|ref|NP_524555.1| CG31039-PA [Drosophila melanogaster]gi|12644135|sp|P17207|SER3_DROME Serine protease 3 precursor (Jonah protein 99Ci) [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(25751021..25751576,25751634..25751896); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF5697 [fly-100309-contam.fasta]
  • Serine protease 3 precursor (Protein Jonah 99Ci) [nr-271106-contam.fasta]
  • Jonah 99Ci CG31039-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE70942p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG31039-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(25751021..25751576,25751634..25751896); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(25751021..25751576,25751634..25751896); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(25751021..25751576,25751634..25751896); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973,FlyMine:FBpp0084877,modMine:FBpp0084877; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(29925912..29926174,29925299..29925854)); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973,FlyMine:FBpp0084877,modMine:FBpp0084877; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(29925912..29926174,29925299..29925854)); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973,FlyMine:FBpp0084877,modMine:FBpp0084877; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0084877 type=protein; loc=3R:complement(join(29925912..29926174,29925299..29925854)); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973,FlyMine:FBpp0084877,modMine:FBpp0084877; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(29925912..29926174,29925299..29925854)); ID=FBpp0084877; name=Jon99Ci-PA; parent=FBgn0003358,FBtr0085511; dbxref=FlyBase:FBpp0084877,FlyBase_Annotation_IDs:CG31039-PA,GB_protein:AAF56973.1,REFSEQ:NP_524555,GB_protein:AAF56973,UniProt/Swiss-Prot:P17207,FlyMine:FBpp0084877,modMine:FBpp0084877; MD5=a1768e828d758fd37e19bc4f0e819dfd; length=272; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 272 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA][NAS]
    digestion [NAS]
    Molecular Function: serine-type endopeptidase activity [ISS][NAS]
    endopeptidase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGLTLLSLA FLGVCSALTV PHSLVHPRDL EIRHGGIEGR ITNGNLASEG QVPYIVGVSL  60
   61 NSNGNWWWCG GSIIGHTWVL TAAHCTAGAD EASLYYGAVN YNEPAFRHTV SSENFIRYPH 120
  121 YVGLDHDLAL IKTPHVDFYS LVNKIELPSL DDRYNSYENN WVQAAGWGAI YDGSNVVEDL 180
  181 RVVDLKVISV AECQAYYGTD TASENTICVE TPDGKATCQG DSGGPLVTKE GDKLIGITSF 240
  241 VSAYGCQVGG PAGFTRVTKY LEWIKEETGI YY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..272] PSI-BLAST 49.30103 HL collagenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  5.91209560688646 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  5.52773635813967 bayes_pls_golite062009
  • serine hydrolase activity
    		•  5.5105092190926 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  5.49703869306079 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  5.39623690248556 bayes_pls_golite062009
  • endopeptidase activity
    		•  5.32070018460528 bayes_pls_golite062009
  • hydrolase activity
    		•  4.40346950809697 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.01328116441763 bayes_pls_golite062009
  • heparin binding
    		•  1.48285358055737 bayes_pls_golite062009
  • thrombospondin receptor activity
    		•  1.44312413043539 bayes_pls_golite062009
  • catalytic activity
    		•  1.40927913545237 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.34665327732001 bayes_pls_golite062009
  • DNA binding
    		•  1.32316407831391 bayes_pls_golite062009
  • binding
    		•  1.30738106455622 bayes_pls_golite062009
  • protein binding
    		•  1.30414885212044 bayes_pls_golite062009
  • fucose binding
    		•  1.28001086938735 bayes_pls_golite062009
  • receptor activity
    		•  1.10676631226741 bayes_pls_golite062009
  • calcium-dependent protein binding
    		•  1.10244132298625 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.03130756227487 bayes_pls_golite062009
  • serine-type aminopeptidase activity
    		•  0.964413112640311 bayes_pls_golite062009
  • signal transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.885246794092463 bayes_pls_golite062009
  • growth factor activity
    		•  0.848900101748605 bayes_pls_golite062009
  • receptor binding
    		•  0.79054390509229 bayes_pls_golite062009
  • sodium channel regulator activity
    		•  0.30724450617383 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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