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Protein Overview: amon-PA

General Information:
Name(s) found: amon-PA / FBpp0084420 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene amontillado is referred to in FlyBase by the symbol Dmel\amon (CG6438, FBgn0023179). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22523418..22539881. It has the cytological map location 97C4-97C5. There is experimental evidence that it has the molecular function</span>: peptidase activity. There is experimental evidence that it is involved in the biological process</span>: instar larval or pupal development; hatching behavior; proteolysis. 21 alleles are reported. The phenotypes of these alleles are annotated with: larval head; leg; dorsal mesothoracic disc; ventral prothoracic disc; ventral metathoracic disc; wing; ventral thoracic disc; ventral mesothoracic disc. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 654 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IDA]
    Biological Process: hatching behavior [IMP]
    proteolysis [IDA]
    peptide hormone processing [ISS]
    instar larval or pupal development [IMP]
    Molecular Function: serine-type endopeptidase activity [ISS]
    peptidase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAATWSWLL APFLLLHWAS AGAGGGAGGS GAGLSGPAVF TSSFLVRFRR GVDNSFAHDV  60
   61 ADKYGFDNLG PLVGADGHEY HFKHRTLPHA RSRRSLTHTR ALKSHPAVHT AVQQPGFKRV 120
  121 KRGLRPAVPA IHGMKFDLKV GEGNRIDEEP TDPYFPMQWY LKNTGQNGGK VRLDLNVQAA 180
  181 WAQGITGKNV TTAIMDDGVD YMHPDLKFNY NAEASYDFSS NDPFPYPRYT DDWFNSHGTR 240
  241 CAGEVAAARD NGICGVGVAY DSKIAGIRML DQPYMTDLIE ANSMGHEPHK IHIYSASWGP 300
  301 TDDGKTVDGP RNATMRAIVQ GVNEGRNGLG NIYVWASGDG GEEDDCNCDG YAASMWTISI 360
  361 NSAINDGQNA HYDESCSSTL ASTFSNGAKD PNTGVATTDL YGKCTTTHSG TSAAAPEAAG 420
  421 VFALALEANP QLTWRDIQHL TVLTSKRNSL FDAKNRFHWT MNGVGLEFNH LFGFGVLDAG 480
  481 AMVTLSKQWH SVPPRYHCEA GELTQPQAIV MGRSLFWEIK TDACKGTDTE VNYLEHVQAV 540
  541 ISANASRRGD LELFLTSPMG TKSMILSRRA NDDDHRDGFT KWPFMTTHSW GEYPQGTWKL 600
  601 EARFNSPQTR HGNLLEWSLV LHGTKEAPYR TLHPSSPHSK LAIVKKAHED KKMK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] PSI-BLAST 36.522879 No description for 2p4eP was found.
    2 View Details [153..654] PSI-BLAST 94.522879 Furin, C-terminal domain; Furin, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  4.77677490610016 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40501322467328 bayes_pls_golite062009
  • serine hydrolase activity
    		•  4.30899317351154 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  4.29545891350519 bayes_pls_golite062009
  • nerve growth factor binding
    		•  3.93556598541015 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.83336601331518 bayes_pls_golite062009
  • serine-type endopeptidase activity
    		•  3.71508033196614 bayes_pls_golite062009
  • neurotrophin binding
    		•  2.36320382357038 bayes_pls_golite062009
  • hydrolase activity
    		•  2.05732080397524 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  1.50287724152407 bayes_pls_golite062009
  • binding
    		•  1.08901362883653 bayes_pls_golite062009
  • catalytic activity
    		•  0.597535457699629 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.42083764849682 bayes_pls_golite062009
  • protein binding
    		•  0.380935140681308 bayes_pls_golite062009
  • receptor binding
    		•  0.222369968782666 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.11649614154172 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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