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Protein Overview: gi|40365347, gi|...

General Information:
Name(s) found: gi|40365347 [NCBI NR]
gi|28572050 [NCBI NR]
gi|28381471 [NCBI NR]
Description(s) found:
Found 10 descriptions.
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  • gi|40365347|gb|AAR85347.1| dysfusion [Drosophila melanogaster] [NCBI NR]
  • gi|28572050|ref|NP_733137.2| dysfusion, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|28381471|gb|AAF56569.3| dysfusion, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 881 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC][IDA]
    protein complex [IPI]
    Biological Process: epithelial cell migration, open tracheal system [IMP]
    signal transduction [IEA]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA][ISS]
    branch fusion, open tracheal system [IEP][IMP]
    positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA]
    regulation of gene-specific transcription from RNA polymerase II promoter [IDA]
    open tracheal system development [IMP][NAS]
    Molecular Function: transcription factor activity [IDA][ISS]
    protein heterodimerization activity [IPI][TAS]
    sequence-specific DNA binding [IDA]
    transcription activator activity [IDA]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYADNKRGLD KVTAATPPTH ALQQQQQQQH PHQQQQHLQH VLQLQQQQQQ HLQQQQHHLQ  60
   61 HQMHTHHNFQ QHETSPTVSQ QQHMQQQQPQ TTQQQHATQQ QQQQQQQTAG MFTRFDANKS 120
  121 TKGASKMRRD LINAEIANLR DLLPLPQSTR QRLSQLQLMA LVCVYVRKAN YFQQVFKRHN 180
  181 AMHHLHHQTA TPNIGFSKAL SGFLMMLTQN GKLLYISDNA AEYLGHSMED LLIHGDSVYD 240
  241 IIDKQDHANI QAELNRNVPP QPGGSSQASS GGAGGAGGAG DSTSSNGSAA GAGGAGGASS 300
  301 LEGEHRMFLC RMNVSRNARR QMRFGDQKVV LVQGHYLSFL PLCSRNEPVF LATCTPIAMP 360
  361 ETRECVVQGA TNVFTTIHSM DMKIAHIDKN GEFHLGYDKS TLQGTSWYNL IHSDNLTEAQ 420
  421 KKHSLIIQSE QDRSCILLVR MQRSSGEYTW VHVVLQVRDS PDSTQQPVIV CTNQVLNDRE 480
  481 ASIMLANSWL YHYYTVQSKI QFGMPLDSGI RVPPGTPSSG YYSPHSSHPP ATPGGATPNL 540
  541 GIASSFGPHH HPHHSHHPHH HHHHHHPATA YHHHPHMGTY GGVYHAKAAI ELKEDQPLFC 600
  601 FQEPVDYSQV NSHVNPPNAT STPNPPISKS STPPPPKKRA RKLEPLYLHA ERSPAAAITP 660
  661 EPDCYAIHTH PAAAYATSSV VSSDASVIYA TIVPTRPRLP NKSLPPDPAD FIEQWNPSPP 720
  721 WSESAQKASL DSFGSSHELS PCITTTPPTP TSATPHQSGL GTTQTIGPAF SFEWMSDPLV 780
  781 PVTYQQWPPT GDHHQHLSQH LSQSQNHQNP LQQQQNEQLL LGQQPHLHQQ HQHLALHHGR 840
  841 GEHSLEGESQ GVVVVPPIPI SIPIPTATGH GDAGEPVEDR G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] FFAS03 1.17 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    2 View Details [109..191] PSI-BLAST 3.39794 Usf B/HLH domain
    3 View Details [192..578] PSI-BLAST 58.0 Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD
    4 View Details [579..687] deduced N/A No confident structure predictions are available.
    5 View Details [688..881] PSI-BLAST 3.30103 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • transcription activator activity
    		•  3.87875547821718 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.42035985454056 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.39500382187264 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.42306484786159 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • promoter binding
    		•  0.8576109846276 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.801830750183111 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle