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Protein Overview: danr-PA

General Information:
Name(s) found: danr-PA / FBpp0084155 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene distal antenna-related is referred to in FlyBase by the symbol Dmel\danr (CG13651, FBgn0039283). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20963799..20965625. It has the cytological map location 96C2. There is experimental evidence that it has the molecular function</span>: transcription factor activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: segment specification; compound eye development; regulation of transcription. 7 alleles are reported. The phenotypes of these alleles are annotated with: unguis; eye; interommatidial bristle; rostral membrane; tarsal segment; wing; arista; ommatidium; antennal segment 3. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chromosome, centromeric region [IEA]
    Biological Process: regulation of transcription [IMP]
    compound eye development [IMP]
    segment specification [IMP]
    Molecular Function: DNA binding [NAS]
    transcription factor activity [IMP]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISAYQHMN IRMSTRGKRP LRNLTPNDKV RAIQRIHNGE TKASVSRDIG VPESTLRGWC  60
   61 KNEQKLRFMC RQLGPDHLGL DTPPEKRAKF ELQLQLPPKF VALPPNYEEL GFGALPYSPA 120
  121 DYPVQNESLL EKLSLVEFVK KNGGLHPEGA LHPGQAGVMD YSNNMLHQLN LLALLNSKLT 180
  181 PQTADVLVDA QPKSEDNKVI DSPAASEDYS KNNYPLLSVK NWAKDPAKRV NSANQPEQVN 240
  241 DKNNNALEAN SSAPQALVTE QAKTPMFSDT TMPLLPAPFP NPADLAPVIA PVTPANAPPT 300
  301 GTDNQGAALL DWCKLFNASL NFLAFAAAAA SMQPGGGGPG GPSYNPNQMA SGGSEPDLET 360
  361 YPFNEALLKR LSPLAHSEAS NESYCDSEPE DLSVRSCASK ASSRSHTPDK SVGSSDAEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..141] PSI-BLAST 28.522879 DNA-binding domain of centromere binding protein B (CENP-B)
    2 View Details [142..263] deduced N/A No confident structure predictions are available.
    3 View Details [264..419] MSA 11.168996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.20953772435302 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  0.876241359231159 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle