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Protein Overview: twin-PC

General Information:
Name(s) found: twin-PC / FBpp0083954 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene twin is referred to in FlyBase by the symbol Dmel\twin (CG31137, FBgn0011725). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20023310..20047687. It has the cytological map location 95F1-95F2. Based on sequence similarity, it is predicted to have molecular function</span>: transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis; nuclear-transcribed mRNA poly(A) tail shortening. 23 alleles are reported. The phenotypes of these alleles are annotated with: nurse cell ring canal; oocyte; egg chamber; nurse cell. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 567 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA][ISS]
    CCR4-NOT complex [ISS]
    Biological Process: oogenesis [IMP]
    nuclear-transcribed mRNA poly(A) tail shortening [IMP]
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [ISS]
    regulation of transcription from RNA polymerase II promoter [ISS]
    Molecular Function: protein binding [IEA]
    transcription regulator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCIFKKRDAY HQAVIMKGNH YKMSRNKDKY DSANRRQQIF LSQEDIAAGK KTNWSGLEIT  60
   61 GCVRNISPSL WEFEHLTALY LNDNQLLRLP ADVGMLTSLR TLDLSSNKLR SLPAELGELI 120
  121 QLRELLLNNN FLRVLPYEIG KLFHLVILGL MGNPLQKEFM NIYNEPNGTQ KLLTYMLDNL 180
  181 SFTVNPPPQR PWLPLAKPNK TRPACIFTVM CYNVLCDKYA TRQMYGYCPS WALCWEYRKK 240
  241 SIIDEIRHYA ADIISLQEIE TEQFYHFFLP ELKNDGYEGI FSPKSRAKTM SELERKYVDG 300
  301 CAIFFRASKF TLIKESLIEF NQLAMANAEG SDNMLNRVMP KDNIGLAALL KVKENAWEPM 360
  361 SEVTQISQPL LVCTAHIHWD PEFCDVKLIQ TMMLSNELKT IIDEASHSFR PGHKNDSNAV 420
  421 QLLLCGDFNS LPDSGVVEFL GKGRVSMDHL DFKDMGYKSC LQRLLSNDTN EFTHSFKLAS 480
  481 AYNEDIMPHT NYTFDFKGII DYIFYTKTGM VPLGLLGPVS NDWLRENKVV GCPHPHIPSD 540
  541 HFPLLVELEL MHTASQQAPP NGLINRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..204] PSI-BLAST 23.522879 No description for 2o6qA was found.
    2 View Details [205..415] PSI-BLAST 9.522879 No description for 2v9sA was found.
    3 View Details [416..567] FFAS03 3.63 No description for 2ddrA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle