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Protein Overview: gi|28572143, gi|...

General Information:
Name(s) found: gi|28572143 [NCBI NR]
gi|23171868 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|28572143|ref|NP_524432.4| Rab-protein 1, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23171868|gb|AAN13857.1| Rab-protein 1, isoform B [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 146 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: regulation of cell shape [IMP]
    negative regulation of dendrite morphogenesis [IMP]
    ER to Golgi vesicle-mediated transport [TAS]
    small GTPase mediated signal transduction [IEA]
    actin filament organization [IMP]
    cell adhesion [IMP]
    protein secretion [IMP]
    Molecular Function: GTP binding [IEA]
    GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSVNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI RTIELDGKTI  60
   61 KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDCTDQESFN NVKQWLEEIE RYACENVNKL 120
  121 LVGNKSDLTT KKVVDHTTAA VRILLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] PSI-BLAST 46.39794 Crystal structure of human RAB1A in complex with GDP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  2.28726855139279 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.23754609668547 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.21702600128327 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.21503003850174 bayes_pls_golite062009
  • binding
    		•  2.00548409930693 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • transporter activity
    		•  1.85044926113762 bayes_pls_golite062009
  • ATPase activity
    		•  1.70670922135201 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.656935231793 bayes_pls_golite062009
  • GTPase activity
    		•  1.23010905798386 bayes_pls_golite062009
  • hydrolase activity
    		•  1.20846280768115 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.02588328213159 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • motor activity
    		•  0.55840571419988 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.464456497491373 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.220911105984699 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.0756212238097211 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0210109380921899 bayes_pls_golite062009
  • actin binding
    		•  0.00459252905837204 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle