Protein Overview: SNF4Agamma-PB, S...

General Information:
Name(s) found:	SNF4Agamma-PB / FBpp0083422 [FlyBase] SNF4Agamma-PA / FBpp0083421 [FlyBase]
Description(s) found: Found 38 descriptions. SHOW ALL	The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dmel\SNF4AĂ?Ă?Âł (CG17299, FBgn0025803). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16966463..17038409. It has the cytological map location 93C1-93C5. Based on sequence similarity, it is predicted to have molecular function</span>: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle; cholesterol homeostasis. 51 alleles are reported. The phenotypes of these alleles are annotated with: adult central complex; trichogen cell; adult central nervous system; tormogen cell; adult brain. It has 16 annotated transcripts and 16 annotated polypeptides. [FlyBase] The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dmel\SNF4AĂ?Ă?Âł (CG17299, FBgn0025803). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16966463..17038409. It has the cytological map location 93C1-93C5. Based on sequence similarity, it is predicted to have molecular function</span>: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle; cholesterol homeostasis. 51 alleles are reported. The phenotypes of these alleles are annotated with: adult central complex; trichogen cell; adult central nervous system; tormogen cell; adult brain. It has 16 annotated transcripts and 16 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	947 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	positive regulation of cell cycle [IGI] protein amino acid phosphorylation [ISS] cholesterol homeostasis [IMP]
Molecular Function:	AMP-activated protein kinase activity [ISS][NAS] protein serine/threonine kinase activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSSAGGASG GSNYEDVAAA RRGRFRVTSS TPQGPPETTL GRFRLMPTSN YGAISPILQR  60
   61 GRFAVIPEEP QAGSPALGTP PPGGRTARSP SPEWDFDIEQ EQDGSLGGAG RMPGSRPSSA 120
  121 PAEPNAKAAK KAYKKMEKEQ RRQEKEQSRR EKEARKLERE TARRNEREAA KLEKINRHSE 180
  181 KISRSTERMA MAGVGSRSGS LERRRSGEDS PVLNQSTVHG IASPNRRPTI FDVFRPRAKS 240
  241 DAKRQKEKHL LDPSSADSSA TSSTYSVSGG TGPATSSAAG GAGGAAAAAG QGAAGGAGGL 300
  301 MNSMKVAMQN FSHRQHPAVT ITSADGTQST AKSKYKDGSA HPHQGSDAQY YHTVTAVRPN 360
  361 SSQRSPMTKV MDLFRHRSSS VVSEADKRKA RAAAHQQQLA VQSAHMRRAS ADLEKRRASV 420
  421 GAAGRGLRGD GTLDPHHAAI LFRDSRGLPV ADPFLEKVNL SDLEEDDSQI FVKFFRFHKC 480
  481 YDLIPTSAKL VVFDTQLLVK KAFYALVYNG VRAAPLWDSE KQQFVGMLTI TDFIKILQMY 540
  541 YKSPNASMEQ LEEHKLDTWR SVLHNQVMPL VSIGPDASLY DAIKILIHSR IHRLPVIDPA 600
  601 TGNVLYILTH KRILRFLFLY INELPKPAYM QKSLRELKIG TYNNIETADE TTSIITALKK 660
  661 FVERRVSALP LVDSDGRLVD IYAKFDVINL AAEKTYNDLD VSLRKANEHR NEWFEGVQKC 720
  721 NLDESLYTIM ERIVRAEVHR LVVVDENRKV IGIISLSDIL LYLVLRPSGE GVGGSESSLR 780
  781 ASDPVLLRKV AEVEIPATAA AATTTTPPRS PSAGSGNRSL IEDIPEEETA PARSDDADSD 840
  841 NNKSASEDKA NNNQHDQTTT AATANGDSNN SPVEVSFADE AQEEEAADQV ERSNCDDDDQ 900
  901 PALAEIERKN ASMDDDEDDG MSSAVSAASA LGQSLTPAAQ EMALVSE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
phosphorylase kinase regulator activity	7.70391834244316	bayes_pls_golite062009
AMP-activated protein kinase activity	7.44642435115105	bayes_pls_golite062009
cAMP-dependent protein kinase inhibitor activity	6.93689873566354	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.56838904228494	bayes_pls_golite062009
protein kinase activity	2.52567871323046	bayes_pls_golite062009
kinase activity	2.4422214009645	bayes_pls_golite062009
cAMP-dependent protein kinase regulator activity	2.35874140792742	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.34602478412267	bayes_pls_golite062009
protein serine/threonine kinase activity	2.17402447573866	bayes_pls_golite062009
transferase activity	1.64817967293013	bayes_pls_golite062009
binding	1.63354691422982	bayes_pls_golite062009
protein binding	1.38803085961368	bayes_pls_golite062009
protein kinase binding	1.35253529418057	bayes_pls_golite062009
kinase binding	1.3320291155323	bayes_pls_golite062009
substrate-specific channel activity	1.31002370375073	bayes_pls_golite062009
ion transmembrane transporter activity	1.26281943988481	bayes_pls_golite062009
ion channel activity	0.956667854360503	bayes_pls_golite062009
channel activity	0.940842319076591	bayes_pls_golite062009
passive transmembrane transporter activity	0.940842319076591	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.929686668465826	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.889901921302766	bayes_pls_golite062009
gated channel activity	0.736786411102643	bayes_pls_golite062009
cation transmembrane transporter activity	0.709718817747483	bayes_pls_golite062009
enzyme binding	0.263336937308997	bayes_pls_golite062009
protein kinase regulator activity	0.254655971647361	bayes_pls_golite062009
kinase regulator activity	0.22192900867037	bayes_pls_golite062009
catalytic activity	0.205284274859133	bayes_pls_golite062009
PDZ domain binding	0.0288055199494393	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.00255895098457382	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..281]	FFAS03	1.2	No description for 2i1jA was found.
2	View Details	[282..451]	deduced	N/A	No confident structure predictions are available.
3	View Details	[452..518]	PSI-BLAST	54.39794	No description for 2v8qE was found.
4	View Details	[519..623]	FFAS03	4.12	Crystal structure of CBS domain-containing predicted protein (TM0935) from Thermotoga maritima at 1.87 A resolution
5	View Details	[624..693]	PSI-BLAST	22.0	No description for 2uv4A was found.
6	View Details	[694..947]	PSI-BLAST	20.69897	Crystal Structure of GuaC (BA5705) from Bacillus anthracis at 1.8 A Resolution

Protein Overview: SNF4Agamma-PB, S...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: