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Protein Overview: Calx-PA, Calx-PC...

General Information:
Name(s) found: Calx-PC / FBpp0083404 [FlyBase]
Calx-PB / FBpp0083403 [FlyBase]
Calx-PA / FBpp0083402 [FlyBase]
Description(s) found:
Found 50 descriptions.
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  • The gene Na/Ca-exchange protein is referred to in FlyBase by the symbol Dmel\Calx (CG5685, FBgn0013995). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16803998..16840182. It has the cytological map location 93A4-93B3. There is experimental evidence that it has the molecular function</span>: calcium:sodium antiporter activity. There is experimental evidence that it is involved in the biological process</span>: phototransduction. 17 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye; eye photoreceptor cell. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Na/Ca-exchange protein is referred to in FlyBase by the symbol Dmel\Calx (CG5685, FBgn0013995). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16803998..16840182. It has the cytological map location 93A4-93B3. There is experimental evidence that it has the molecular function</span>: calcium:sodium antiporter activity. There is experimental evidence that it is involved in the biological process</span>: phototransduction. 17 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye; eye photoreceptor cell. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Na/Ca-exchange protein is referred to in FlyBase by the symbol Dmel\Calx (CG5685, FBgn0013995). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16803998..16840182. It has the cytological map location 93A4-93B3. There is experimental evidence that it has the molecular function</span>: calcium:sodium antiporter activity. There is experimental evidence that it is involved in the biological process</span>: phototransduction. 17 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye; eye photoreceptor cell. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 950 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    plasma membrane [ISS]
    Biological Process: transmembrane transport [IEA]
    cell communication [IEA]
    calcium ion transport [IEA]
    phototransduction [IMP]
    Molecular Function: calcium:sodium antiporter activity [IDA][IMP][ISS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLLLKSIFT CALFVIFVYA TAQSLLKVQE TEARQAYLNV TSSSSSNLSQ DDGHFLSRRL  60
   61 RQVSHGEEGD EGAPSQMDDE LEQMTKVHGE APDAEELREC SEGLVLPLWM PQRNISVGDR 120
  121 LVRGFVYFVL LIYLFVGVSI IADRFMAAIE AITSIERAVV VKGPNNTKQV MHVRIWNETV 180
  181 ANLTLMALGS SAPEILLSVI EIYAKDFESG DLGPGTIVGS AAYNLFMIIA VCMIWIPAGE 240
  241 VRRIRHLRVF FVTALFSVFA YVWLWLILSV FTPGVILVWE AIVTLLFFPL TVLWAYIAER 300
  301 RLLVYKYMDK NYRVNKRGTV VAGEHDQVEM DAEKGPKQPM VTSARGNDAE AFDEARREYI 360
  361 TLLTELRQKY PDADLEQLEM MAQEQVLARS SKSRAFYRIQ ATRKMVGSGN LMRKIQERAH 420
  421 SDLTEVKAQL HAGDDEEADD PIRMYFEPGH YTVMENCGEF EVRVVRRGDI STYASVEYET 480
  481 QDGTASAGTD FVGRKGLLSF PPGVDEQRFR IEVIDDDVFE EDECFYIRLF NPSEGVKLAV 540
  541 PMIATVMILD DDHAGIFAFT DSVFEITESV GRFELKVMRY SGARGTVIVP YWTENDTATE 600
  601 SKDYEGARGE LVFENNESEK FIDLFILEES SYEKDVSFKV HIGEPRLAPD DELAAKIKEV 660
  661 EKKPVQDLTE LDRILLLSKP RNGELTTAYV RIRESQEFKA TVDKLVAKAN VSAVLGTSSW 720
  721 KEQFKDALTV IPADESEFDN DDEEEEVPSC FSYVSHFVCL FWKVLFAFVP PTDICGGYVT 780
  781 FVVSIFVIGV ITAIIGDAAS YFGCALNIKD SVTAILFVAL GTSIPDTFAS MIAAKHDEGA 840
  841 DNCIGNVTGS NAVNVFLGIG LAWTIAAVYH SSHGMTFNVE PGTIGFAVAL FCGEALIAIM 900
  901 LIMFRRWHKG IGAELGGPKV SKYISAAILV FLWVFYVVIC ILEAYDVIRV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..146] MSA 1.166997 View MSA. No confident structure predictions are available.
    2 View Details [147..309] Pfam 30.180456 No description for PF01699.15 was found. No confident structure predictions are available.
    3 View Details [310..390] deduced N/A No confident structure predictions are available.
    4 View Details [391..552] PSI-BLAST 34.045757 No description for 2dpkA was found.
    5 View Details [553..721] PSI-BLAST 28.0 No description for 2fwuA was found.
    6 View Details [722..769] deduced N/A No confident structure predictions are available.
    7 View Details [770..950] Pfam 31.677781 No description for PF01699.15 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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