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Protein Overview: repo-PA

General Information:
Name(s) found: repo-PA / FBpp0082986 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene reversed polarity is referred to in FlyBase by the symbol Dmel\repo (CG31240, FBgn0011701). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14061916..14065326. It has the cytological map location 90F9-90F10. It is reported to have molecular function</span>: RNA polymerase II transcription factor activity. It is reported to be involved in the biological process</span>: glial cell differentiation; regulation of transcription from RNA polymerase II promoter. 30 alleles are reported. The phenotypes of these alleles are annotated with: glial cell; embryonic glial cell; ventral nerve cord; retina; PNS glial cell; interface glial cell; longitudinal connective; medial-most cell body glial cell; lamina anlage; lateral cord glia. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA][NAS]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA]
    glial cell differentiation [NAS]
    regulation of transcription from RNA polymerase II promoter [NAS]
    Molecular Function: transcription factor activity [IEA]
    RNA polymerase II transcription factor activity [NAS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEHDSFDDPI FGEFGGGPLN PLGAKPLMPT TTAMHPVMLG SVHELCSQQQ QQQQQQRLPD  60
   61 CNTILPNGGG GGAGSGGAGG SPNYVTKLDF VNKMGCYSPS QKYEYISAPQ KLVEQQQQQQ 120
  121 HHHQHHQHYT ATPPPSHNGI LLHKQSSQQQ QQQQQQLVGI LDYHPLNGKL DYSSSPKDQY 180
  181 EPQQLQHLYG GSPHHLDHLD HGSDGLLQDS SPVMINGGSA GGKLKKPDEM CSQLEAGGAG 240
  241 VTPPSSSSTV VNGTTNGTGN ANSSSSAGVG IQGAAGTAGG VAAPAAKKDG SSSKKKGDPN 300
  301 GIKKKKTRTT FTAYQLEELE RAFERAPYPD VFAREELAIK LNLSESRVQV WFQNRRAKWR 360
  361 KHEPPRKTGY IKTSTPPTAT LNPGTLAPPF TSYPQTTTVT PPGSMDSWTS YQTPYELTPQ 420
  421 FSLLSPAASP YGTYSGQYGA YVHESQLFPM RHYEYGSPTR MEMGATTGSV AGNGDESVAN 480
  481 GGSYQTAELQ TAQQQQLADG TLVTVHAHQQ QQQQQQQLNG KYLSAEEAKY VHLQCHQSGG 540
  541 GLELSPGASC HLVEAQGQHY VTTATGGAAS AGGTSSDDND SGGMQTVIKS EEVSQQQQQQ 600
  601 QGQSYVLPPF LH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] FFAS03 1.15 Mgcm1
    2 View Details [75..285] deduced N/A No confident structure predictions are available.
    3 View Details [286..367] PSI-BLAST 15.154902 Paired protein
    4 View Details [368..612] MSA 3.228974 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.334577365229545 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0696342306231097 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle